4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Base Information

Chemical Name:4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde
CAS No.:1450841-36-7
Molecular Formula:C₂₆H₂₉NO₄Si
Molecular Weight:447.606
Hs Code.:

Synonyms:4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Suppliers and Price of 4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

There total 4 articles about 4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 1450841-35-6
(4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-diyl)dimethanol

: 1450841-36-7
4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Guidance literature:: (4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-diyl)dimethanol; With oxalyl dichloride; dimethyl sulfoxide; In dichloromethane; at -78 ℃; for 0.5h; Inert atmosphere;

With triethylamine; In dichloromethane; at -78 - 20 ℃;
DOI:10.1039/c3cc44354j

Reference yield:

: 1450841-34-5
dimethyl 4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarboxylate

: 1450841-36-7
4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium borohydride / tetrahydrofuran; methanol / 0 - 50 °C

2.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

2.2: -78 - 20 °C

With lithium borohydride; oxalyl dichloride; dimethyl sulfoxide; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1039/c3cc44354j

Reference yield:

: chelidamic acid

: 1450841-36-7
4-(3-((tert-butyldiphenylsilyl)oxy)propoxy)pyridine-2,6-dicarbaldehyde

Guidance literature:: Multi-step reaction with 4 steps

1.1: thionyl chloride / 24 h / 50 °C

2.1: triphenylphosphine; di-isopropyl azodicarboxylate / tetrahydrofuran / 0 - 20 °C

3.1: lithium borohydride / tetrahydrofuran; methanol / 0 - 50 °C

4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C / Inert atmosphere

4.2: -78 - 20 °C

With lithium borohydride; thionyl chloride; oxalyl dichloride; di-isopropyl azodicarboxylate; dimethyl sulfoxide; triphenylphosphine; In tetrahydrofuran; methanol; dichloromethane;
DOI:10.1039/c3cc44354j