Technology Process of C36H41ClFN3O6
There total 5 articles about C36H41ClFN3O6 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: N-ethyl-N,N-diisopropylamine; tetrabutylammomium bromide / 1,4-di(diphenylphosphino)-butane; palladium diacetate / N,N-dimethyl-formamide / 30 h / 140 °C
2.1: trifluoroacetic acid / dichloromethane / 0.25 h / 20 °C
2.2: 1.5 h / 40 °C
2.3: 1.7percent palladium-fibroin / 18 h / 20 °C
3.1: potassium tert-butylate / tetrahydrofuran / 0.5 h
4.1: lithium hexamethyldisilazane / hexane; tetrahydrofuran / 0.67 h / -20 °C
4.2: 2 h / -20 - 0 °C
5.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -78 - 0 °C
5.3: 5 h / 20 °C
With
trimethylsilyl trifluoromethanesulfonate; potassium tert-butylate; tetrabutylammomium bromide; N-ethyl-N,N-diisopropylamine; trifluoroacetic acid; lithium hexamethyldisilazane;
palladium diacetate; 1,4-di(diphenylphosphino)-butane;
In
tetrahydrofuran; hexane; dichloromethane; N,N-dimethyl-formamide;
1.1: Heck Reaction;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogen / palladium 10% on activated carbon / ethanol / 7 h / 20 °C
2.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -78 - 0 °C
2.3: 5 h / 20 °C
With
trimethylsilyl trifluoromethanesulfonate; hydrogen;
palladium 10% on activated carbon;
In
ethanol; dichloromethane;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: diisopropyl-carbodiimide / copper(l) chloride / 96 h / 20 °C / Darkness
1.2: 4.5 h / 60 °C
2.1: hydrogen / palladium 10% on activated carbon / ethanol / 7 h / 20 °C
3.1: trimethylsilyl trifluoromethanesulfonate / dichloromethane / 1 h / -78 - 0 °C
3.3: 5 h / 20 °C
With
trimethylsilyl trifluoromethanesulfonate; hydrogen; diisopropyl-carbodiimide;
palladium 10% on activated carbon; copper(l) chloride;
In
ethanol; dichloromethane;