Technology Process of 3-(4-acetoxy-5-oxo-3-phenyl-2,5-dihydro-furan-2-yl)propionic acid
There total 12 articles about 3-(4-acetoxy-5-oxo-3-phenyl-2,5-dihydro-furan-2-yl)propionic acid which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
acetic anhydride;
In
pyridine;
- Guidance literature:
-
Multi-step reaction with 11 steps
1: 97 percent / NaH / tetrahydrofuran / Ambient temperature
2: 99 percent / MCPBA / CH2Cl2 / Ambient temperature
3: EtONa / ethanol / Heating
4: 80 percent / aq. NaOH / Heating
5: 77 percent / Me2NH, AcONa / acetic acid / 100 °C
6: 42 percent / OsO4,NaIO4 / dioxane / Ambient temperature
7: 96 percent / H2 / Pd-black / ethanol
8: 92 percent / Et3N / tetrahydrofuran / 0 °C
9: 96 percent / CrO3, H2SO4 / acetone; H2O / 0 °C
10: 71 percent / K2CO3 / methanol; H2O / Ambient temperature
11: pyridine
With
pyridine; chromium(VI) oxide; sodium periodate; osmium(VIII) oxide; sulfuric acid; hydrogen; sodium ethanolate; sodium acetate; sodium hydride; potassium carbonate; dimethyl amine; triethylamine; 3-chloro-benzenecarboperoxoic acid;
palladium;
In
tetrahydrofuran; 1,4-dioxane; methanol; sodium hydroxide; ethanol; dichloromethane; water; acetic acid; acetone;
DOI:10.1016/S0040-4039(00)84436-6
- Guidance literature:
-
Multi-step reaction with 10 steps
1: 99 percent / MCPBA / CH2Cl2 / Ambient temperature
2: EtONa / ethanol / Heating
3: 80 percent / aq. NaOH / Heating
4: 77 percent / Me2NH, AcONa / acetic acid / 100 °C
5: 42 percent / OsO4,NaIO4 / dioxane / Ambient temperature
6: 96 percent / H2 / Pd-black / ethanol
7: 92 percent / Et3N / tetrahydrofuran / 0 °C
8: 96 percent / CrO3, H2SO4 / acetone; H2O / 0 °C
9: 71 percent / K2CO3 / methanol; H2O / Ambient temperature
10: pyridine
With
pyridine; chromium(VI) oxide; sodium periodate; osmium(VIII) oxide; sulfuric acid; hydrogen; sodium ethanolate; sodium acetate; potassium carbonate; dimethyl amine; triethylamine; 3-chloro-benzenecarboperoxoic acid;
palladium;
In
tetrahydrofuran; 1,4-dioxane; methanol; sodium hydroxide; ethanol; dichloromethane; water; acetic acid; acetone;
DOI:10.1016/S0040-4039(00)84436-6
