(R)-4-benzylmorpholine-2-carboxyester

Base Information

• Chemical Name: (R)-4-benzylmorpholine-2-carboxyester
• CAS No.: 1401233-92-8
• Molecular Formula: C₁₃H₁₇NO₃
• Molecular Weight: 235.283
• Mol file: 1401233-92-8.mol

Synonyms:(R)-4-benzylmorpholine-2-carboxyester

Chemical Property of (R)-4-benzylmorpholine-2-carboxyester

Chemical Property:

Purity/Quality:

98% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-4-benzylmorpholine-2-carboxyester

There total 2 articles about (R)-4-benzylmorpholine-2-carboxyester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 93.0%

methyl 4-benzylmorpholine-2-carboxylate (135782-29-5) → (R)-4-benzylmorpholine-2-carboxyester (1401233-92-8)

Guidance literature:

With Methyl Tertiary-Butyl Ether Water; for 12h;

Reference yield:

4-benzylmorpholine-2-carboxylic acid hydrochloride (135072-15-0) → (R)-4-benzylmorpholine-2-carboxyester (1401233-92-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sulfuric acid / 12 h / Reflux

2: Methyl Tertiary-Butyl Ether Water / 12 h

With sulfuric acid; Methyl Tertiary-Butyl Ether Water;

Reference yield:

(R)-4-benzylmorpholine-2-carboxyester (1401233-92-8) → (R)-4-benzylmorpholine-2-carboxylic acid hydrochloride (1401233-93-9)

Guidance literature:

(R)-4-benzylmorpholine-2-carboxyester; With water; lithium hydroxide; In tetrahydrofuran; methanol; at 20 ℃; for 12h;

With hydrogenchloride; In water; pH=5;

upstream raw materials:

4-benzylmorpholine-2-carboxylic acid hydrochloride

methyl 4-benzylmorpholine-2-carboxylate

Downstream raw materials:

(R)-4-benzylmorpholine-2-carboxylic acid hydrochloride

Refernces