CID 6992295

Base Information

• Chemical Name: CID 6992295
• CAS No.: 7298-84-2
• Molecular Formula: C9H18N2O3
• Molecular Weight: 202.254
• Hs Code.: 2924199090
• Mol file: 7298-84-2.mol

Synonyms:

Chemical Property of CID 6992295

Chemical Property:

• Appearance/Colour: white powder
• Melting Point: 255-256 °C (decomp)
• Refractive Index: 19 ° (C=5, MeOH)
• Boiling Point: 409.7 °C at 760 mmHg
• PKA: 3.16±0.10(Predicted)
• Flash Point: 201.6 °C
• PSA: 92.42000
• Density: 1.108 g/cm³
• LogP: 1.04030
• Storage Temp.: 2-8°C
• XLogP3: -2.4
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 3
• Rotatable Bond Count: 4
• Exact Mass: 202.13174244
• Heavy Atom Count: 14
• Complexity: 211

Purity/Quality:

98%,99%, ^*data from raw suppliers

Leu-Ala-OH ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC(C)CC(C(=O)NC(C)C(=O)[O-])[NH3+]
• Isomeric SMILES: C[C@@H](C(=O)[O-])NC(=O)[C@H](CC(C)C)[NH3+]
• Uses: ubiquitin blocker, neurite growth inhibitor This dipeptide inhibits ubiquitin-mediated protein degradation. (2S)-2-[[(2S)-2-Azaniumyl-4-methylpentanoyl]amino]propanoate is used in muscle synthesis promoting agent comprising whey protein Hydrolyzate.

Technology Process of CID 6992295

There total 14 articles about CID 6992295 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

N-(benzyloxycarbonyl)-L-leucyl-L-alanine phenylmethyl ester (17664-94-7) → Leu-Ala (7298-84-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In methanol; for 24h; Ambient temperature;

Reference yield: 94.0%

L-alanine lithium salt + L-leucine lithium salt → Leu-Ala (7298-84-2)

Guidance literature:

Multistep reaction;

Reference yield: 84.7%

L-alanin (56-41-7,25191-17-7,18875-37-1) + L-Leucin-N-carbonsaeureanhydrid (3190-70-3,26334-33-8,51018-87-2,51248-35-2) → Leu-Ala (7298-84-2) + N-carbamoylglycine (462-60-2)

Guidance literature:

With potassium hydroxide; potassium borate buffer; In water; at 3 ℃; pH 10.2;

upstream raw materials:

((S)-2-(benzyloxycarbonylamino)-4-methylpentanamido)propanoic acid

L-alanin

L-Leucin-N-carbonsaeureanhydrid

H-Leu-Ala-Pro-OH

Downstream raw materials:

(3S,6S)-3-methyl-6-(2-methylpropyl)piperazine-2,5-dione

1-hippuroyl-L-proline

Refernces

• 1、 -. "Compositions and Methods for Binding Lysophosphatidic Acid". . . Retrieved 2009/06/27.
• 2、 Li,Sung Tsai Lin,Jian Hsiu Yang. "An expedient N-terminal attachment methodology for the solid phase peptide synthesis". . p. 1608 - 1612. Retrieved 2007/10/03.