4-(4-Methylpiperazine-1-carbonyl)benzonitrile

Base Information

Chemical Name:4-(4-Methylpiperazine-1-carbonyl)benzonitrile
CAS No.:1000932-49-9
Molecular Formula:C₁₃H₁₅N₃O
Molecular Weight:229.282
Hs Code.:
DSSTox Substance ID:DTXSID901240525

Synonyms:4-(4-methylpiperazine-1-carbonyl)benzonitrile;1000932-49-9;4-[(4-methylpiperazin-1-yl)carbonyl]benzonitrile;4-[(4-methyl-1-piperazinyl)carbonyl]- Benzonitrile;SCHEMBL13504026;DTXSID901240525;AKOS000199510;EN300-30988;4-[(4-Methyl-1-piperazinyl)carbonyl]benzonitrile

Suppliers and Price of 4-(4-Methylpiperazine-1-carbonyl)benzonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(4-Methylpiperazine-1-carbonyl)benzonitrile

Chemical Property:

XLogP3:0.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:1
Exact Mass:229.121512110
Heavy Atom Count:17
Complexity:317

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CN1CCN(CC1)C(=O)C2=CC=C(C=C2)C#N

Technology Process of 4-(4-Methylpiperazine-1-carbonyl)benzonitrile

There total 1 articles about 4-(4-Methylpiperazine-1-carbonyl)benzonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 68.0%

: 109-01-3
1-methyl-piperazine

: 105-07-7
4-cyanobenzaldehyde

: 1000932-49-9
4-(4-methylpiperazine-1-carbonyl)benzonitrile

Guidance literature:: With 2,8-dibromo-5,5-difluoro-1,3,7,9-tetramethyl-10-phenyl-5H-dipyrrolo[1,2-c:2′,1′-f ][1,3,2]diazaborinin-4-ium-5-uide; 2,6-di-tert-butyl-4-methyl-phenol; oxygen; In 1,4-dioxane; at 25 ℃; for 48h; Sealed tube; Irradiation; Green chemistry;
DOI:10.1039/c6ob00736h

Reference yield: 73.0%

: 110-91-8,99108-56-2
morpholine

: 141-84-4
2-thioxo-4-thiazolidinone

: 1000932-49-9
4-(4-methylpiperazine-1-carbonyl)benzonitrile

: 16781-67-2
2-morpholin-4-yl-2-thiazole-4(5H)-one

: 1429057-94-2
4-((4-methylpiperazine-1-yl)carbothioyl)benzonitrile

Guidance literature:: With MCM-41 mesoporous silica; In ethanol; water; at 80 - 90 ℃; for 9h; Green chemistry;
DOI:10.1016/j.tetlet.2013.02.045

Reference yield: 50.0%

: 1000932-49-9
4-(4-methylpiperazine-1-carbonyl)benzonitrile

: 2⁽¹³⁾CN^(1-)*Zn⁽²⁺⁾

: [13CN]-4-(4-methylpiperazine-1-carbonyl)benzonitrile

Guidance literature:: With dmap; bis(1,5-cyclooctadiene)nickel⁽⁰⁾; trimethylphosphane; In toluene; at 130 ℃; for 12h; Glovebox; Sealed tube;
DOI:10.1021/jacs.1c01923