2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol

Base Information

• Chemical Name: 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol
• CAS No.: 1418220-64-0
• Molecular Formula: C₂₄H₁₄N₂O₃
• Molecular Weight: 378.387
• Mol file: 1418220-64-0.mol

Synonyms:2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol

Chemical Property of 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol

There total 5 articles about 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 58.0%

1-amino-3-(1,3-benzoxazol-2-yl)naphthalen-2-ol (1418220-62-8) + salicylic acid (69-72-7,25496-36-0,8052-31-1) → 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol (1418220-64-0)

Guidance literature:

With phosphorus trichloride; In chlorobenzene; at 130 - 133 ℃;

DOI:10.1016/j.tet.2012.11.095

Reference yield:

3-(1,3-benzoxazol-2-yl)naphthalen-2-ol (14967-45-4) → 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol (1418220-64-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: sodium carbonate; sodium nitrite; hydrogenchloride / water / 2 h / 0 - 55 °C

1.2: 4 h / 0 - 20 °C / pH 8 - 9

2.1: sodium hydroxide; sodium dithionate / water / 2.5 h / 50 - 90 °C / pH 8 - 9

3.1: phosphorus trichloride / chlorobenzene / 130 - 133 °C

With hydrogenchloride; sodium dithionate; sodium carbonate; sodium hydroxide; sodium nitrite; phosphorus trichloride; In water; chlorobenzene;

DOI:10.1016/j.tet.2012.11.095

Reference yield:

4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid (1418220-58-2) → 2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol (1418220-64-0)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; sodium dithionate / water / 2.5 h / 50 - 90 °C / pH 8 - 9

2: phosphorus trichloride / chlorobenzene / 130 - 133 °C

With sodium dithionate; sodium hydroxide; phosphorus trichloride; In water; chlorobenzene;

DOI:10.1016/j.tet.2012.11.095

upstream raw materials:

3-(1,3-benzoxazol-2-yl)naphthalen-2-ol

4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid

1-amino-3-(1,3-benzoxazol-2-yl)naphthalen-2-ol

salicylic acid