4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid

Base Information

• Chemical Name: 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid
• CAS No.: 1418220-58-2
• Molecular Formula: C₂₃H₁₅N₃O₅S
• Molecular Weight: 445.455
• Mol file: 1418220-58-2.mol

Synonyms:4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid

Chemical Property of 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid

There total 2 articles about 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

3-(1,3-benzoxazol-2-yl)naphthalen-2-ol (14967-45-4) + 4-aminobenzene sulfonic acid (121-57-3,856062-06-1) → 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid (1418220-58-2)

Guidance literature:

4-aminobenzene sulfonic acid; With hydrogenchloride; sodium carbonate; sodium nitrite; In water; at 0 - 55 ℃; for 2h;

3-(1,3-benzoxazol-2-yl)naphthalen-2-ol; In water; at 0 - 20 ℃; for 4h; pH=8 - 9;

DOI:10.1016/j.tet.2012.11.095

Reference yield:

2-amino-phenol (95-55-6) → 4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid (1418220-58-2)

Guidance literature:

Multi-step reaction with 2 steps

1.1: phosphorus trichloride / chlorobenzene / 4 h / 133 - 135 °C

2.1: sodium carbonate; sodium nitrite; hydrogenchloride / water / 2 h / 0 - 55 °C

2.2: 4 h / 0 - 20 °C / pH 8 - 9

With hydrogenchloride; sodium carbonate; sodium nitrite; phosphorus trichloride; In water; chlorobenzene;

DOI:10.1016/j.tet.2012.11.095

Reference yield:

4-{[3-(1,3-benzoxazol-2-yl)-2-hydroxynaphthalen-1-yl]diazenyl}benzenesulphonic acid (1418220-58-2) → 4-(1,3-benzoxazol-2-yl)-2-phenylnaphtho[1,2-d][1,3]oxazole (1432475-85-8)

Guidance literature:

Multi-step reaction with 2 steps

1: sodium hydroxide; sodium dithionite / water / 2.5 h / 50 - 90 °C / pH 8 - 9

2: dimethyl sulfoxide / 10 h / 158 - 160 °C

With sodium dithionite; sodium hydroxide; In water; dimethyl sulfoxide;

DOI:10.1007/s12039-012-0324-3

upstream raw materials:

3-(1,3-benzoxazol-2-yl)naphthalen-2-ol

4-aminobenzene sulfonic acid

2-amino-phenol

Downstream raw materials:

2-((4-benzo[d]oxazol-2-yl)naphtho[1,2-d]oxazol-2-yl)phenol

4-(1,3-benzoxazol-2-yl)-2-phenylnaphtho[1,2-d][1,3]oxazole

4-(1,3-benzoxazol-2-yl)-2-(3-phenoxyphenyl)naphtho[1,2-d][1,3]oxazole

4-[4-(1,3-benzoxazol-2-yl)naphtho[1,2-d][1,3]oxazol-2-yl]phenol