1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone

Base Information

Chemical Name:1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone
CAS No.:20622-21-3
Molecular Formula:C₁₉H₁₆N₂O
Molecular Weight:288.349
Hs Code.:
NSC Number:118954
DSSTox Substance ID:DTXSID00274921
ChEMBL ID:CHEMBL1607632

Synonyms:1,2-diphenyl-2-(pyridin-2-ylamino)ethanone;20622-21-3;Ethanone, 1,2-diphenyl-2-(2-pyridinylamino)-;NSC118954;1,2-Diphenyl-2-(pyridin-2-ylamino)-ethanone;Oprea1_660371;Oprea1_751662;MLS000689225;CHEMBL1607632;DTXSID00274921;HMS1691I01;HMS2718B22;STK943810;AKOS000530499;AKOS016088588;NSC-118954;NCGC00245316-01;SMR000283219;SR-01000314974;SR-01000314974-1

Suppliers and Price of 1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone

Chemical Property:

Vapor Pressure:1.2E-09mmHg at 25°C
Boiling Point:487.3°C at 760 mmHg
Flash Point:248.5°C
Density:1.203g/cm³
XLogP3:4.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:288.126263138
Heavy Atom Count:22
Complexity:345

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC=C(C=C1)C(C(=O)C2=CC=CC=C2)NC3=CC=CC=N3

Technology Process of 1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone

There total 5 articles about 1,2-Diphenyl-2-(pyridin-2-ylamino)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

: 41855-95-2
N,N¹--α,α-diaminotoluene

: 100-52-7
benzaldehyde

: 20622-21-3
1,2-diphenyl-2-(2-pyridinylamino)ethanone

Guidance literature:: With 4,5-dimethyl-3-(2,4,6-trimethylphenyl)thiazol-3-ium perchlorate; triethylamine; In tetrahydrofuran; for 24h; Inert atmosphere; Reflux; Automated synthesizer;
DOI:10.1021/acs.joc.1c00973

Reference yield:

: 504-29-0
2-aminopyridine

: 119-53-9,579-44-2
2-hydroxy-2-phenylacetophenone

: 20622-21-3
1,2-diphenyl-2-(2-pyridinylamino)ethanone

Guidance literature:: With hydrogenchloride; toluene;
DOI:10.1021/ja01099a509

Reference yield:

: 100-52-7
benzaldehyde

: 20622-21-3
1,2-diphenyl-2-(2-pyridinylamino)ethanone

Guidance literature:: Multi-step reaction with 2 steps

1: toluene / 24 h / 70 °C / Molecular sieve; Inert atmosphere; Automated synthesizer

2: 4,5-dimethyl-3-(2,4,6-trimethylphenyl)thiazol-3-ium perchlorate; triethylamine / tetrahydrofuran / 24 h / Inert atmosphere; Reflux; Automated synthesizer

With 4,5-dimethyl-3-(2,4,6-trimethylphenyl)thiazol-3-ium perchlorate; triethylamine; In tetrahydrofuran; toluene;
DOI:10.1021/acs.joc.1c00973