(2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

Base Information

Chemical Name:(2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine
CAS No.:936092-57-8
Molecular Formula:C₁₂H₈Cl₂F₃N₃
Molecular Weight:322.117
Hs Code.:

Synonyms:(2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

Suppliers and Price of (2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

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Technology Process of (2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

There total 1 articles about (2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

: 445-01-2
5-bromo-2-chlorobenzotrifluoride

: 14394-70-8
2-chloro-4-amino-5-methylpyrimidine

: 936092-57-8
(2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

Guidance literature:: With caesium carbonate; tris-(dibenzylideneacetone)dipalladium⁽⁰⁾; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; In 1,4-dioxane; N,N-dimethyl-formamide; at 160 ℃; for 0.25h; Product distribution / selectivity; Microwave irradiation;

Reference yield: 20.0%

: 936092-57-8
(2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine

: 138227-63-1
tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate

: N₄-(4-chloro-3-trifluoromethyl-phenyl)-5-methyl-N₂-[4-(piperidin-4-yloxy)-phenyl]-pyrimidine-2,4-diamine

Guidance literature:: (2-chloro-5-methyl-pyrimidin-4-yl)-(4-chloro-3-trifluoromethyl-phenyl)-amine; tert-butyl 4-(4-aminophenoxy)piperidine-1-carboxylate; With acetic acid; at 150 ℃; for 0.25h; Microwave irradiation;

With sodium hydroxide; In water;