beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid

Base Information

Chemical Name:beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid
CAS No.:120757-14-4
Molecular Formula:C₁₈H₂₄N₂O₄
Molecular Weight:332.4
Hs Code.:
DSSTox Substance ID:DTXSID901221169

Synonyms:DTXSID901221169;beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid;120757-14-4

Suppliers and Price of beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid

Chemical Property:

XLogP3:-1.1
Hydrogen Bond Donor Count:2
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:7
Exact Mass:332.17360725
Heavy Atom Count:24
Complexity:452

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(=O)NC1=CC=C(C=C1)C(=O)C(CC(=O)O)CN2CCCCC2

Technology Process of beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid

There total 1 articles about beta-[4-(Acetylamino)benzoyl]-1-piperidinebutanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.0%

: 110-89-4
piperidine

: 50-00-0,30525-89-4,61233-19-0
formaldehyd

: 5473-15-4
4-(4-acetamidophenyl)-4-oxobutanoic acid

: 120757-14-4
3-(4-acetamidobenzoyl)-4-(N-piperidinyl)butanoic acid

Guidance literature:: In water; 1) room temperature, overnight, 2) steam bath, 2 h;
DOI:10.1002/jhet.5570250615

Reference yield:

: 120757-14-4
3-(4-acetamidobenzoyl)-4-(N-piperidinyl)butanoic acid

: 36725-28-7
6-(4-aminophenyl)-4,5-dihydro-5-methyl-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 5 steps

1: conc. H₂SO₄ / 1 h / Heating

2: pyridine

3: H₂ / Raney Nickel / methanol / 0.33 h / 1034.3 Torr

4: 90 percent / hydrazine hydrate / ethanol; H₂O / 2 h / Heating

5: 76 percent / 1 M aq. HCl / 1.25 h / Heating

With pyridine; hydrogenchloride; sulfuric acid; hydrogen; hydrazine hydrate; nickel; In methanol; ethanol; water;
DOI:10.1002/jhet.5570250615

Reference yield:

: 120757-14-4
3-(4-acetamidobenzoyl)-4-(N-piperidinyl)butanoic acid

: 112127-66-9
5-methyl-6-[4-(4-oxo-1,4-dihydropyridin-1-yl)phenyl]-4,5-dihydro-3(2H)-pyridazinone

Guidance literature:: Multi-step reaction with 6 steps

1: conc. H₂SO₄ / 1 h / Heating

2: pyridine

3: H₂ / Raney Nickel / methanol / 0.33 h / 1034.3 Torr

4: 90 percent / hydrazine hydrate / ethanol; H₂O / 2 h / Heating

5: 76 percent / 1 M aq. HCl / 1.25 h / Heating

With pyridine; hydrogenchloride; sulfuric acid; hydrogen; hydrazine hydrate; nickel; In methanol; ethanol; water;
DOI:10.1002/jhet.5570250615