5473-15-4

Usage

Classification

Nonsteroidal anti-inflammatory drug (NSAID)

Function

Reduces pain and inflammation

Mechanism of Action

Inhibits the production of certain inflammatory chemicals in the body

Medical Uses

Treatment of arthritis, muscle pain, menstrual cramps

Administration

Can be prescribed alone or in combination with other medications

Precautions

Should be used with caution and under the guidance of a healthcare professional

Potential Side Effects

Varied and may include gastrointestinal issues, kidney problems, allergic reactions

Interactions

Can interact with other medications; healthcare professional guidance necessary for safe usage.

InChI:InChI=1/C12H13NO4/c1-8(14)13-10-4-2-9(3-5-10)11(15)6-7-12(16)17/h2-5H,6-7H2,1H3,(H,13,14)(H,16,17)

Upstream product

• 108-30-5 succinic acid anhydride 
• 103-84-4 Acetanilid 
• 62-53-3 aniline 
• 110-15-6 succinic acid 
• 24849-50-1 4-(4-acetylaminophenyl)-4-oxo-but-2-enoic acid 

Downstream Products

• 120757-14-4 3-(4-acetamidobenzoyl)-4-(N-piperidinyl)butanoic acid 
• 52240-85-4 4-(4-amino-phenyl)-4-oxo-butyric acid,methyl ester 
• 305-03-3 chlorambucil 
• 15118-60-2 4-(4-aminophenyl)butyric Acid 
• 205759-94-0 methyl 4-(p-aminophenyl)butyrate 
• 130198-76-4 methyl 3-<4-phenyl>butyrate 
• 79481-83-7 methyl 4-(4-(bis(2-chloroethyl)amino)phenyl)butanoate 
• 85221-80-3 6-[p-(acetylamino)phenyl]-4,5-dihydro-2-methyl-3(2H)-pyridazinone 
• 95355-15-0 4-(4-acetylaminobenzoyl)-2(3H)-dihydrofuranone 
• 6945-94-4 4-(4-amino-phenyl)-4-oxo-butyric acid 
• 55901-89-8 4-(4-acetylamino-3-nitro-phenyl)-4-oxo-butyric acid 
• 760179-19-9 N-(4-{4-[1-(4-Cyano-phenyl)-meth-(E)-ylidene]-5-oxo-4,5-dihydro-furan-2-yl}-phenyl)-acetamide 
• 21394-91-2 N-(4-(6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl)acetamide 
• 132544-78-6 [3-(4-Acetylamino-phenyl)-6-oxo-5,6-dihydro-4H-pyridazin-1-yl]-acetic acid ethyl ester 

Relevant academic research and scientific papers

A process for synthesizing phenylbutyric acid nitrogen mustard antineoplastic agent

The invention relates to a synthesis process of an antineoplastic drug chlorambucil. The synthesis process comprises the following steps: (1) amino protection reaction; (2) acylation reaction; (3) reduction reaction; (4) carboxyl protection reaction; (5) substitution reaction; (6) chlorination reaction; and (7) deprotection reaction. According to the synthesis process, the amino group is protected by use of acetic anhydride, and then acylation, reduction, carboxyl protection, substitution, chlorination and aqueous hydrochloric acid solution hydrolysis are performed to obtain the chlorambucil. The synthesis process of the antineoplastic drug chlorambucil has the characteristics of low cost, mild reaction conditions, low toxicity, convenience in process operation, and suitability for industrial production.

Derivatives of 4-hydroxybutanoic acid and of its higher homologue as ligands of γ(g)-hydroxybutyrate (ghb) receptors, pharmaceutical compositions containing same and pharmaceutical uses

The invention concerns the field of synthesis organic chemistry applied to the pharmaceutical field and concerns novel derivatives of 4-hydroxybutanoic acid and its higher homologue, 5-hydroxypentanoic acid, their crotonic homologues, pharmaceutical compo

Benzene butyric acids and their derivatives as inhibitors of matrix metalloproteinases

Benzene butyric acid compounds and derivatives are described as well as methods for the preparation and pharmaceutical compositions of same, which are useful as inhibitors of matrix metalloproteinases, particularly gelatinase A, collagenase-3, and stromel