Picloram

Base Information

• Chemical Name: Picloram
• CAS No.: 1918-02-1
• Molecular Formula: C6H3Cl3N2O2
• Molecular Weight: 241.461
• Hs Code.: 2933399990
• European Community (EC) Number: 217-636-1
• ICSC Number: 1246
• NSC Number: 233899
• UNII: O7437X49DW
• DSSTox Substance ID: DTXSID1021160
• Nikkaji Number: J3.383I
• Wikipedia: Picloram
• Wikidata: Q424662
• ChEMBL ID: CHEMBL461349
• Mol file: 1918-02-1.mol

Synonyms:Chloramp;Picloram

Chemical Property of Picloram

Chemical Property:

• Appearance/Colour: fine beige crystals or white powder
• Melting Point: 215 °C
• Refractive Index: 1.6770 (estimate)
• Boiling Point: 420.5 °C at 760 mmHg
• PKA: 4.1(at 25℃)
• Flash Point: 208.1 °C
• PSA: 76.21000
• Density: 1.811 g/cm³
• LogP: 2.90340
• Storage Temp.: 0-6°C
• Solubility.: Soluble in acetone
• Water Solubility.: 420 mg/L
• XLogP3: 2.2
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 239.926010
• Heavy Atom Count: 13
• Complexity: 216

Purity/Quality:

99.9% ^*data from raw suppliers

Picloram ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi
• Statements: 36
• Safety Statements: 26

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Chemical Classes: Pesticides -> Herbicides, Other
• Canonical SMILES: C1(=C(C(=NC(=C1Cl)Cl)C(=O)O)Cl)N
• Inhalation Risk: Evaporation at 20 °C is negligible; a nuisance-causing concentration of airborne particles can, however, be reached quickly on spraying or when dispersed, especially if powdered.
• Effects of Long Term Exposure: The substance may have effects on the liver.
• Description: Picloram is a colourless crystal. It is very soluble in acetone, ethanol, benzene, and dichloromethane. It is a systemic herbicide used for general woody plant control, sold under the trade names Tordon and Grazon. It also controls a wide range of broad-leaved weeds, but most grasses are resistant. It is used in formulations with other herbicides such as bromoxynil, diuron, 2,4-D, MCPA, triclorpyr, and atrazine. It is also compatible with fertilisers. Picloram, in the pyridine family of compounds, is a systemic herbicide used for control of woody plants and a wide range of broad-leaved weeds. Most grasses are resistant to picloram, so it is used in range management programs. Picloram is formulated either as an acid (technical product), a potassium or triisopropanolamine salt, or an isooctyl ester, and is available as either soluble concentrates, pellets, or granular formulations. The materials in this document refer to the technical acid form unless otherwise indicated. Picloram is stable under acidic, neutral and basic conditions. Picloram is formulated either as an acid (technical product), a potassium or triisopropanolamine salt, or an isooctyl ester, and is available as either soluble concentrates, pellets, or granular formulations and related manufacturing impurities.
• Uses: Systemic herbicide used to control most broad-leaved weeds on grassland and noncrop areas. Use as a pesticide is restricted It is used as a herbicide and defoliant. Herbicide. Picloram is a dicot-selective, persistent herbicide and in salt form is used to control a variety of annual weeds on crops, perennial broadleaved herbs, and woody species in combination with 2,4-D or 2,4,5-T. It can persist in an active form in the soil from several months to years, and can also be released from the roots of treated plants into the soil, where other nontarget species may take it up and die. Picloram is of great use in the management of unwanted vegetation in rangeland, grass pastures, and forestry as well as non-cropland and rightsof- way sites, such as around industrial and military installations, roads, railways, airports, under power lines, and along pipelines. Additional uses in some countries include in rice, sugarcane, cereals, and oilseed rape.

Technology Process of Picloram

There total 7 articles about Picloram which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.3%

4-amino-3,5,6-trichloro-2-trichloromethylpyridine (5005-62-9) → 4-amino-2,3,5-trichloropyridine (28443-69-8) + picloram (1918-02-1)

Guidance literature:

With sulfuric acid; trichloroacetic acid; In water; at 110 ℃; for 10h;

Reference yield:

ammonium hydroxide (1336-21-6) + 3,4,5,6-tetrachloropicolinonitrile (17824-83-8) → picloram (1918-02-1)

Guidance literature:

With ammonia;

Reference yield:

aminopyralid (150114-71-9) → 4-amino-3,6-dichloro-5-fluoropyridine-2-carboxylic acid + picloram (1918-02-1)

Guidance literature:

With Selectfluor; In water; at 25 - 65 ℃;

DOI:10.1016/j.tetlet.2009.10.089

upstream raw materials:

4-amino-3,5,6-trichloro-2-trichloromethylpyridine

ammonium hydroxide

3,4,5,6-tetrachloropicolinonitrile

aminopyralid

Refernces

• 1、 -. "NOXIOUS ARTHROPOD CONTROL AGENT CONTAINING AMIDE COMPOUND". . . Retrieved 2017/08/26.
• 2、 -. "Methods for protecting ZEA mays plants against pest damage". . . Retrieved 2008/06/13.