p-Hydroxy-d-amphetamine

Base Information

Chemical Name:p-Hydroxy-d-amphetamine
CAS No.:1693-66-9
Molecular Formula:C9H13 N O
Molecular Weight:151.208
Hs Code.:2922299090
Mol file:1693-66-9.mol

Synonyms:Phenol,4-(2-aminopropyl)-, (S)-; Phenol, p-(2-aminopropyl)-, (+)- (8CI);(+)-Paredrine; (+)-p-Hydroxyamphetamine; (S)-p-Hydroxyamphetamine;d-Hydroxyamphetamine; d-p-Hydroxyamphetamine; p-Hydroxy-D-amphetamine

Suppliers and Price of p-Hydroxy-d-amphetamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
(+)-Paredrine
100mg
$ 1470.00

American Custom Chemicals Corporation
(+)-PAREDRINE 95.00%
5MG
$ 456.18

Total 0 raw suppliers

Chemical Property of p-Hydroxy-d-amphetamine

Chemical Property:

Vapor Pressure:0.0024mmHg at 25°C
Boiling Point:279.2°C at 760 mmHg
Flash Point:122.7°C
PSA：46.25000
Density:1.07g/cm³
LogP:1.98220

Purity/Quality:: (+)-Paredrine ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Uses Paredrine is a metabolite of (S)-Amphetamine (A634245), a CNS stimulant; anorexic. More active isomer of Amphetamine. Induces release of catecholamines and serotonin by displacing the monoamines from their vesicular storage sites; blocks catecholamine reuptake.Controlled substance (stimulant).

Technology Process of p-Hydroxy-d-amphetamine

There total 8 articles about p-Hydroxy-d-amphetamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 735231-40-0
C₁₇H₂₁NO

: 1518-89-4,1518-86-1
(-)-Hydroxyamphetamine

: 1693-66-9,1518-86-1
(+)-Hydroxyamphetamine

Guidance literature:: With palladium 10% on activated carbon; hydrogen; In methanol; at 45 ℃; for 8h; Reagent/catalyst; Autoclave;

Reference yield: 67.0%

: 3938-96-3
ethyl 2-methoxyacetate

: 103-86-6,1518-86-1
p-hydroxyamphetamine

: 1351781-81-1
C₁₂H₁₇NO₃

: 1518-89-4,1518-86-1
(-)-Hydroxyamphetamine

: 1693-66-9,1518-86-1
(+)-Hydroxyamphetamine

Guidance literature:: With Candida antartica lipase B; triethylamine; at 35 ℃; for 96h; optical yield given as %ee; Inert atmosphere; Enzymatic reaction;
DOI:10.1039/c1ob06251d

Reference yield:

: 17354-63-1
4-(2-nitro-propenyl)-anisole

: 1518-89-4,1518-86-1
(-)-Hydroxyamphetamine

: 1693-66-9,1518-86-1
(+)-Hydroxyamphetamine

Guidance literature:: Multi-step reaction with 3 steps

1: lithium aluminium tetrahydride / diethyl ether / 3 h / Inert atmosphere; Reflux

2: hydrogen bromide / water / 3 h / Reflux

3: Candida antartica lipase B; triethylamine / 96 h / 35 °C / Inert atmosphere; Enzymatic reaction

With lithium aluminium tetrahydride; Candida antartica lipase B; hydrogen bromide; triethylamine; In diethyl ether; water;
DOI:10.1039/c1ob06251d