(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

Base Information

Chemical Name:(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester
CAS No.:349148-54-5
Molecular Formula:C₂₅H₂₃NO₄
Molecular Weight:401.462
Hs Code.:

Synonyms:(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

Suppliers and Price of (2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

There total 1 articles about (2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 67.0%

: 55135-66-5
9-bromo-9-phenyl-9H-fluorene

: (2S,3R)-2-amino-4-methoxy-3-methyl-4-oxobutanoic acid

: 349148-54-5
(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

Guidance literature:: (2S,3R)-2-amino-4-methoxy-3-methyl-4-oxobutanoic acid; With chloro-trimethyl-silane; In chloroform; for 2h;

9-bromo-9-phenyl-9H-fluorene; With lead(II) nitrate; triethylamine; In chloroform; for 72h; Further stages.;
DOI:10.1021/jo0014055

Reference yield: 73.0%

: 71432-55-8
2-tert-butyl-1,3-diisopropylisourea

: 349148-54-5
(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

: 120230-43-5
(2S,3R)-N-(9-phenylfluoren-9-yl)-3-methyl-aspartic acid 1-tert-butyl 4-methyl diester

Guidance literature:: In dichloromethane; at 20 ℃; for 48h;
DOI:10.1021/jo0014055

Reference yield:

: 349148-54-5
(2S,3R)-2-Methyl-3-(9-phenyl-9H-fluoren-9-ylamino)-succinic acid 1-methyl ester

: 120230-47-9
tert-butyl (2S,3R)-2-<(9-phenylfluorenyl)amino>-3-methyl-4-hydroxybutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 73 percent / CH₂Cl₂ / 48 h / 20 °C

2: 80 percent / DIBAL / tetrahydrofuran / 6 h / -30 °C

With diisobutylaluminium hydride; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jo0014055