9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

Base Information

Chemical Name:9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine
CAS No.:544671-68-3
Molecular Formula:C₃₂H₃₂F₆N₄O₃
Molecular Weight:634.621
Hs Code.:

Synonyms:9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

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Chemical Property of 9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

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Technology Process of 9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

There total 4 articles about 9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1347698-77-4
C₃₀H₃₀F₆N₄O₂

: 75-36-5
acetyl chloride

: 544671-68-3
9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

Guidance literature:: With triethylamine; In tetrahydrofuran; at 0 - 20 ℃; for 0.5h;

Reference yield:

: C₃₅H₃₈F₆N₄O₄

: 544671-68-3
9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

Guidance literature:: Multi-step reaction with 2 steps

1: hydrogenchloride / ethyl acetate / 1 h / 20 °C

2: triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; ethyl acetate;

Reference yield:

: 73874-95-0
(piperidin-4-yl)carbamic acid tert-butyl ester

: 544671-68-3
9-[4-(acetylamino)piperidine-1-yl]-5-[3,5-bis(trifluoromethyl)benzyl]-7-(2-methylphenyl)-6-oxo-2,3,4,5-tetrahydro-6H-pyrido[2,3-b][1,5]oxazocine

Guidance literature:: Multi-step reaction with 3 steps

1: 3 h / 150 °C

2: hydrogenchloride / ethyl acetate / 1 h / 20 °C

3: triethylamine / tetrahydrofuran / 0.5 h / 0 - 20 °C

With hydrogenchloride; triethylamine; In tetrahydrofuran; ethyl acetate;