tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate

Base Information

• Chemical Name: tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate
• CAS No.: 1593267-93-6
• Molecular Formula: C₂₄H₂₆O₃
• Molecular Weight: 362.469
• Mol file: 1593267-93-6.mol

Synonyms:tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate

Chemical Property of tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate

There total 2 articles about tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

4-tert-Butylphenylacetylene (772-38-3) + tert-butyl 3-bromobenzoate (69038-74-0) + 9-methyl-9H-fluorene-9-carbonyl chloride (82102-37-2) → tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate (1593267-93-6)

Guidance literature:

With dichloro(1,5-cyclooctadiene)palladium(II); N-Methyldicyclohexylamine; triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride; tri tert-butylphosphoniumtetrafluoroborate; In 1,4-dioxane; at 80 ℃; for 16h; Inert atmosphere; Glovebox; Sealed tube;

DOI:10.1021/ol5007289

Reference yield: 94.0%

carbon monoxide (201230-82-2) + 4-tert-Butylphenylacetylene (772-38-3) + tert-butyl 3-bromobenzoate (69038-74-0) → tert-butyl 3-(3-(4-(tert-butyl)phenyl)prop-2-ynoyl)benzoate (1593267-93-6)

Guidance literature:

With triethylamine; 4,5-bis(diphenylphosphino)-9,9-dimethylxanthene; palladium dichloride; In 1,4-dioxane; at 80 ℃; for 16h; Sealed tube; Inert atmosphere;

DOI:10.1021/acs.orglett.5b01250

upstream raw materials:

4-tert-Butylphenylacetylene

tert-butyl 3-bromobenzoate

9-methyl-9H-fluorene-9-carbonyl chloride

carbon monoxide