4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether

Base Information

• Chemical Name: 4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether
• CAS No.: 79787-59-0
• Molecular Formula: C₁₅H₂₂O₃
• Molecular Weight: 250.338
• Mol file: 79787-59-0.mol

Synonyms:4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether

Chemical Property of 4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether

There total 1 articles about 4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

C17H24O4 (1227743-08-9) → 4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether (79787-59-0)

Guidance literature:

With sodium ethanolate; In ethanol; for 4h;

DOI:10.1016/j.tetlet.2010.02.113

Reference yield: 61.0%

4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether (79787-59-0) + N-(all-trans-Retinoyl)-imidazole (61319-45-7) → (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester (79787-58-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;

DOI:10.1021/jm00343a016

Reference yield:

4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether (79787-59-0) → 4-hydroxy-3-tert-butylphenyl retinoate (79787-60-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 61 percent / K₂CO₃ / dimethylformamide / 4 h / Ambient temperature

2: 85 percent / p-TsOH / methanol / 24 h / Ambient temperature

With potassium carbonate; toluene-4-sulfonic acid; In methanol; N,N-dimethyl-formamide;

DOI:10.1021/jm00343a016

upstream raw materials:

C₁₇H₂₄O₄

Downstream raw materials:

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester

4-hydroxy-3-tert-butylphenyl retinoate