(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester

Base Information

• Chemical Name: (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester
• CAS No.: 79787-58-9
• Molecular Formula: C₃₅H₄₈O₄
• Molecular Weight: 532.764
• Mol file: 79787-58-9.mol

Synonyms:(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester

Chemical Property of (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester

There total 1 articles about (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 61.0%

4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether (79787-59-0) + N-(all-trans-Retinoyl)-imidazole (61319-45-7) → (2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester (79787-58-9)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; for 4h; Ambient temperature;

DOI:10.1021/jm00343a016

Reference yield: 85.0%

(2E,4E,6E,8E)-3,7-Dimethyl-9-(2,6,6-trimethyl-cyclohex-1-enyl)-nona-2,4,6,8-tetraenoic acid 3-tert-butyl-4-(tetrahydro-pyran-2-yloxy)-phenyl ester (79787-58-9) → 4-hydroxy-3-tert-butylphenyl retinoate (79787-60-3)

Guidance literature:

With toluene-4-sulfonic acid; In methanol; for 24h; Ambient temperature;

DOI:10.1021/jm00343a016

upstream raw materials:

4-hydroxy-2-tert-butylphenyl tetrahydropyranyl ether

N-(all-trans-Retinoyl)-imidazole

Downstream raw materials:

4-hydroxy-3-tert-butylphenyl retinoate