ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate

Base Information

• Chemical Name: ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate
• CAS No.: 1620143-44-3
• Molecular Formula: C₁₂H₁₃Cl₃O₄
• Molecular Weight: 327.592
• Mol file: 1620143-44-3.mol

Synonyms:ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate

Chemical Property of ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate

There total 2 articles about ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

2-methoxy-α-(trichloromethyl)benzyl alcohol (58369-59-8) + chloroformic acid ethyl ester (541-41-3) → ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate (1620143-44-3)

Guidance literature:

With triethylamine; In chloroform; at 0 - 30 ℃;

DOI:10.1016/j.tetlet.2014.05.097

Reference yield:

ortho-anisaldehyde (135-02-4) → ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate (1620143-44-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene / 0 - 30 °C

2: triethylamine / chloroform / 0 - 30 °C

With 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; In chloroform;

DOI:10.1016/j.tetlet.2014.05.097

Reference yield: 80.0%

ethyl [2,2,2-trichloro-1-(2-methoxyphenyl)ethyl]carbonate (1620143-44-3) → 1-(2,2-dichlorovinyl)-2-methoxybenzene (56772-78-2)

Guidance literature:

With [2,2]bipyridinyl; copper(l) chloride; In 1,2-dichloro-ethane; for 4h; Reflux; Inert atmosphere; Schlenk technique;

DOI:10.1016/j.tetlet.2014.05.097

upstream raw materials:

2-methoxy-α-(trichloromethyl)benzyl alcohol

chloroformic acid ethyl ester

ortho-anisaldehyde

Downstream raw materials:

1-(2,2-dichlorovinyl)-2-methoxybenzene