2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Base Information

Chemical Name:2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester
CAS No.:96428-70-5
Molecular Formula:C₂₁H₂₄N₂O₃
Molecular Weight:352.433
Hs Code.:

Synonyms:2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Suppliers and Price of 2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

There total 3 articles about 2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 31.0%

: 3282-30-2
pivaloyl chloride

: 79707-34-9
3-(hydroxymethyl)-2-methyl-8-(phenylmethoxy)imidazo<1,2-a>pyridine

: 96428-70-5
2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Guidance literature:: With triethylamine; In dichloromethane; for 3h;
DOI:10.1021/jm00145a006

Reference yield:

: 24016-03-3
2-amino-3-benzyloxypyridine

: 96428-70-5
2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 28 percent / ethanol / 20 h / Heating

2: 65 percent / lithium aluminum hydride / tetrahydrofuran / 1 h / 0 - 5 °C

3: 31 percent / triethylamine / CH₂Cl₂ / 3 h

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; ethanol; dichloromethane;
DOI:10.1021/jm00145a006

Reference yield:

: 96428-50-1
2-carboethoxy-3-methyl-8-(phenylmethoxy)imidazo<1,2-a>pyridine

: 96428-70-5
2,2-Dimethyl-propionic acid 8-benzyloxy-2-methyl-imidazo[1,2-a]pyridin-3-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1: 65 percent / lithium aluminum hydride / tetrahydrofuran / 1 h / 0 - 5 °C

2: 31 percent / triethylamine / CH₂Cl₂ / 3 h

With lithium aluminium tetrahydride; triethylamine; In tetrahydrofuran; dichloromethane;
DOI:10.1021/jm00145a006