3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Base Information

Chemical Name:3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester
CAS No.:366814-56-4
Molecular Formula:C₄₉H₄₅NO₆
Molecular Weight:743.899
Hs Code.:

3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2<i>H</i>-pyridine-1-carboxylic acid 9<i>H</i>-fluoren-9-ylmethyl ester

Synonyms:3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Suppliers and Price of 3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

There total 3 articles about 3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

: 366814-58-6
(2R,3R,4S,5R)-3,4,5-Tris-benzyloxy-2-benzyloxymethyl-6-hydroxy-piperidine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

: 366814-56-4
3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: With oxalyl dichloride; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2001-16049

Reference yield:

: 28920-43-6
(fluorenylmethoxy)carbonyl chloride

: 366814-56-4
3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: aq. K₂CO₃ / tetrahydrofuran / 0 °C

2.1: O₃ / CH₂Cl₂ / -78 °C

2.2: 86 percent / PPh₃ / CH₂Cl₂

3.1: 94 percent / (COCl)2 / CH₂Cl₂; dimethylformamide

With oxalyl dichloride; potassium carbonate; ozone; In tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2001-16049

Reference yield:

: 366814-57-5
((1R,2R,3R,4S)-2,3,4-Tris-benzyloxy-1-benzyloxymethyl-hex-5-enyl)-carbamic acid 9H-fluoren-9-ylmethyl ester

: 366814-56-4
3,4,5-tris-benzyloxy-2-benzyloxymethyl-3,4-dihydro-2H-pyridine-1-carboxylic acid 9H-fluoren-9-ylmethyl ester

Guidance literature:: Multi-step reaction with 2 steps

1.1: O₃ / CH₂Cl₂ / -78 °C

1.2: 86 percent / PPh₃ / CH₂Cl₂

2.1: 94 percent / (COCl)2 / CH₂Cl₂; dimethylformamide

With oxalyl dichloride; ozone; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1055/s-2001-16049