Technology Process of (E)-3-(benzyldimethylsilyl)-2-methylacrylaldehyde
There total 3 articles about (E)-3-(benzyldimethylsilyl)-2-methylacrylaldehyde which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
manganese(IV) oxide;
In
dichloromethane;
at 20 ℃;
for 0.166667h;
DOI:10.1021/ol701427k
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: ethylmagnesium bromide / tetrahydrofuran / 10 - 25 °C / Inert atmosphere
1.2: 2 h / 5 - 70 °C / Inert atmosphere
2.1: copper(l) iodide / tetrahydrofuran; diethyl ether / 21 h / 40 °C / Inert atmosphere
3.1: manganese(IV) oxide; sodium carbonate / dichloromethane / 1.5 h / 0 - 25 °C / Inert atmosphere
With
manganese(IV) oxide; copper(l) iodide; ethylmagnesium bromide; sodium carbonate;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1039/d0ob01084g
- Guidance literature:
-
Multi-step reaction with 2 steps
1: copper(l) iodide / tetrahydrofuran; diethyl ether / 21 h / 40 °C / Inert atmosphere
2: manganese(IV) oxide; sodium carbonate / dichloromethane / 1.5 h / 0 - 25 °C / Inert atmosphere
With
manganese(IV) oxide; copper(l) iodide; sodium carbonate;
In
tetrahydrofuran; diethyl ether; dichloromethane;
DOI:10.1039/d0ob01084g
