(2R)-2-(5-benzoylthiophen-2-yl)propanoic acid

Base Information

Chemical Name:(2R)-2-(5-benzoylthiophen-2-yl)propanoic acid
CAS No.:103667-49-8
Molecular Formula:C14H12 O3 S
Molecular Weight:260.313
Hs Code.:

Synonyms:2-Thiopheneaceticacid, 5-benzoyl-a-methyl-,(R)-; (+)-Tiaprofenic acid; (R)-Tiaprofenic acid; RU 40518

Suppliers and Price of (2R)-2-(5-benzoylthiophen-2-yl)propanoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 2 raw suppliers

Chemical Property of (2R)-2-(5-benzoylthiophen-2-yl)propanoic acid

Chemical Property:

Vapor Pressure:6.8E-09mmHg at 25°C
Boiling Point:450.3°C at 760 mmHg
Flash Point:226.1°C
Density:1.29g/cm³

Purity/Quality:: 99% ，98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of (2R)-2-(5-benzoylthiophen-2-yl)propanoic acid

There total 2 articles about (2R)-2-(5-benzoylthiophen-2-yl)propanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5-benzoyl-2-vinylthiophene

: 201230-82-2
carbon monoxide

: 103667-49-8
(R)-2-(5-benzoylthiophen-2-yl)propanoic acid

: 103667-50-1
(S)-2-(5-benzoylthiophen-2-yl)propanoic acid

Guidance literature:: 5-benzoyl-2-vinylthiophene; carbon monoxide; With hydrogen; acetylacetonatodicarbonylrhodium(l); In benzene; at 60 ℃; under 7500.75 Torr;

With sodium chlorite; sodium dihydrogenphosphate; 2-methyl-but-2-ene; In tetrahydrofuran; tert-butyl alcohol; benzene; at 20 ℃; for 0.5h; Further stages. Title compound not separated from byproducts.;
DOI:10.1021/jo0712190

Reference yield:

: 32990-41-3
2-(5-benzoyl-2-thienyl)propanoic acid methyl ester

: 103667-49-8
(R)-2-(5-benzoylthiophen-2-yl)propanoic acid

: 103667-50-1
(S)-2-(5-benzoylthiophen-2-yl)propanoic acid

Guidance literature:: With sodium hydroxide; In water; at 40 ℃; for 1.5h; Yield given. Yields of byproduct given. Title compound not separated from byproducts; titrisol buffer pH 8, carboxylesterase NP;
DOI:10.1002/recl.19921111104