octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

Base Information

• Chemical Name: octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside
• CAS No.: 187139-97-5
• Molecular Formula: C₃₃H₅₈O₈Si₂
• Molecular Weight: 638.99
• Mol file: 187139-97-5.mol

Synonyms:octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

Chemical Property of octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

There total 4 articles about octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 18.0%

benzoyl chloride (98-88-4) + octyl 4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187139-95-3) → octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187139-97-5) + octyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187140-00-7)

Guidance literature:

In pyridine; for 24h; Ambient temperature;

DOI:10.1016/S0008-6215(96)00215-7

Reference yield:

octanol (111-87-5) → octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187139-97-5)

Guidance literature:

Multi-step reaction with 4 steps

1: 48 percent / SnCl₄, 4A molecular sieves / CH₂Cl₂ / 17 h / Ambient temperature

2: 2.20 g / NaOMe / methanol / 16 h / Ambient temperature

3: 3.38 g / imidazole / CH₂Cl₂; dimethylformamide / 0.25 h

4: 45 percent / pyridine / 24 h / Ambient temperature

With 1H-imidazole; 4 A molecular sieve; sodium methylate; tin(IV) chloride; In pyridine; methanol; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(96)00215-7

Reference yield:

octyl α-D-mannopyranoside (124650-29-9) → octyl 2-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside (187139-97-5)

Guidance literature:

Multi-step reaction with 2 steps

1: 3.38 g / imidazole / CH₂Cl₂; dimethylformamide / 0.25 h

2: 45 percent / pyridine / 24 h / Ambient temperature

With 1H-imidazole; In pyridine; dichloromethane; N,N-dimethyl-formamide;

DOI:10.1016/S0008-6215(96)00215-7

upstream raw materials:

benzoyl chloride

octyl 4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

octanol

octyl α-D-mannopyranoside

Downstream raw materials:

octyl 2,3-di-O-benzoyl-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannopyranoside

octyl 2-O-benzoyl-3-O-(2,3,4,6-tetra-O-benzyl-α-D-galactopyranosyl)-4,6-O-(1,1,3,3-tetraisopropyl-1,3-disiloxane-1,3-diyl)-α-D-mannospyranoside

octyl (2,3,4,6-tetra-O-benzoyl-α-D-mannopyranosyl)-(1->6)-2,3-di-O-benzoyl-α-D-mannopyranoside

octyl 2,3-di-O-benzoyl-4-O-(1-fluoro-1,1,3,3-tetraisopropyl-1,3-disiloxane-3-yl)-α-D-mannopyranoside