3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

Base Information

Chemical Name:3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate
CAS No.:1163693-71-7
Molecular Formula:C₂₁H₂₁F₃O₅
Molecular Weight:410.39
Hs Code.:

Synonyms:3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

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Technology Process of 3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

There total 2 articles about 3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1163693-69-3
3-hydroxy-2-(hydroxymethyl)-2-methylpropyl 4-methylbenzoate

: 329-15-7
4-trifluoromethyl-phenyl acetyl chloride

: 1163693-71-7
3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

Guidance literature:: With N,N,N,N,-tetramethylethylenediamine; In dichloromethane; at -78 ℃; for 0.5h;
DOI:10.1021/ol900828x

Reference yield: 74.0%

: 1163693-67-1
2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate

: 1163693-71-7
3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

Guidance literature:: With tetrabutylammonium tetrafluoroborate; In 1-methyl-pyrrolidin-2-one; isopropyl alcohol; at 90 ℃; chemoselective reaction; Electrochemical reaction;
DOI:10.1021/ol900828x