2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate

Base Information

• Chemical Name: 2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate
• CAS No.: 1163693-67-1
• Molecular Formula: C₃₀H₂₃F₉O₆
• Molecular Weight: 650.495
• Mol file: 1163693-67-1.mol

Synonyms:2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate

Chemical Property of 2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate

There total 1 articles about 2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate (1163693-71-7) + 3,5-bis(trifluoromethyl)phenyl carboxylic acid chloride (785-56-8) → 2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate (1163693-67-1)

Guidance literature:

With N,N,N,N,-tetramethylethylenediamine; In dichloromethane; at -78 ℃; for 0.5h;

DOI:10.1021/ol900828x

Reference yield: 87.0%

2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate (1163693-67-1) + acetic anhydride (108-24-7) → 1,1,1-Tris(acetoxymethyl)ethane (13431-59-9)

Guidance literature:

2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate; With N,N,N,N,N,N-hexamethylphosphoric triamide; samarium diiodide; In tetrahydrofuran; Reflux; Inert atmosphere;

acetic anhydride; With dmap; triethylamine;

DOI:10.1016/j.tet.2009.09.111

Reference yield: 74.0%

2-methyl-3-(4-methylbenzoyloxy)-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 3,5-bis(trifluoromethyl)benzoate (1163693-67-1) → 3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate (1163693-71-7)

Guidance literature:

With tetrabutylammonium tetrafluoroborate; In 1-methyl-pyrrolidin-2-one; isopropyl alcohol; at 90 ℃; chemoselective reaction; Electrochemical reaction;

DOI:10.1021/ol900828x

upstream raw materials:

3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

3,5-bis(trifluoromethyl)phenyl carboxylic acid chloride

Downstream raw materials:

3-hydroxy-2-(hydroxymethyl)-2-methylpropyl 4-methylbenzoate

3-hydroxy-2-methyl-2-((4-(trifluoromethyl)benzoyloxy)methyl)propyl 4-methylbenzoate

2-(hydroxymethyl)-2-methylpropane-1,3-diol

1,1,1-Tris(acetoxymethyl)ethane