1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Base Information

Chemical Name:1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene
CAS No.:291520-39-3
Molecular Formula:C₁₄H₂₆O₃
Molecular Weight:242.359
Hs Code.:

Synonyms:1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Suppliers and Price of 1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

There total 5 articles about 1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 9-((1R,5R,6R)-6-Dimethoxymethyl-5-isopropyl-2-methyl-cyclohex-2-enylmethyl)-9-bora-bicyclo[3.3.1]nonane

: 291520-39-3
1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In tetrahydrofuran; water; at 0 - 20 ℃; for 1.25h;
DOI:10.1016/S0040-4020(00)00309-4

Reference yield:

: 2244-16-8,6485-40-1
(S)-p-mentha-6,8-dien-2-one

: 291520-39-3
1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Guidance literature:: Multi-step reaction with 5 steps

1: 93 percent / H₂; (PPh₃)3RhCl / benzene

2: 61 percent / TiCl₄; DIPEA / CH₂Cl₂ / -78 - 0 °C

3: 71 percent / tetrahydrofuran / 20 h / Heating

4: tetrahydrofuran / 20 h / 45 °C

5: 10.40 g / H₂O₂; NaOH / tetrahydrofuran; H₂O / 1.25 h / 0 - 20 °C

With sodium hydroxide; Wilkinson's catalyst; hydrogen; dihydrogen peroxide; titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water; benzene; 1: Catalytic hydrogenation / 2: Alkylation / 3: methenylation / 4: Addition / 5: Oxidation;
DOI:10.1016/S0040-4020(00)00309-4

Reference yield:

: 499-71-8
carvotanacetone

: 291520-39-3
1-methyl-(4R)-isopropyl-(5R)-dimethyl acetal-6(S)-hydroxymethyl-1-cyclohexene

Guidance literature:: Multi-step reaction with 4 steps

1: 61 percent / TiCl₄; DIPEA / CH₂Cl₂ / -78 - 0 °C

2: 71 percent / tetrahydrofuran / 20 h / Heating

3: tetrahydrofuran / 20 h / 45 °C

4: 10.40 g / H₂O₂; NaOH / tetrahydrofuran; H₂O / 1.25 h / 0 - 20 °C

With sodium hydroxide; dihydrogen peroxide; titanium tetrachloride; N-ethyl-N,N-diisopropylamine; In tetrahydrofuran; dichloromethane; water; 1: Alkylation / 2: methenylation / 3: Addition / 4: Oxidation;
DOI:10.1016/S0040-4020(00)00309-4