Stanozolol

Base Information

• Chemical Name: Stanozolol
• CAS No.: 10418-03-8
• Deprecated CAS: 17966-55-1,69353-49-7,875293-72-4,302-96-5
• Molecular Formula: C21H32N2O
• Molecular Weight: 328.498
• Hs Code.: 29372900
• European Community (EC) Number: 233-894-8
• NSC Number: 43193
• UNII: 4R1VB9P8V3
• DSSTox Substance ID: DTXSID3044128
• Nikkaji Number: J332.003K,J3.432K
• Wikipedia: Stanozolol
• Wikidata: Q417219
• NCI Thesaurus Code: C842
• Pharos Ligand ID: TCP3J6JMNPCA
• Metabolomics Workbench ID: 38252
• ChEMBL ID: CHEMBL2079587
• Mol file: 10418-03-8.mol

Synonyms:Androstanazol;Methylstanazol;Stanazolol;Stanozolol;Stromba;Winstrol

Chemical Property of Stanozolol

Chemical Property:

• Appearance/Colour: white to light yellow powder
• Vapor Pressure: 1.89E-10mmHg at 25°C
• Melting Point: 242 °C
• Refractive Index: 34 ° (C=0.4, CHCl3)
• Boiling Point: 490.8 °C at 760 mmHg
• PKA: 15.15±0.60(Predicted)
• Flash Point: 250.7 °C
• PSA: 48.91000
• Density: 1.129 g/cm³
• LogP: 4.11810
• Storage Temp.: 2-8°C
• Solubility.: Practically insoluble in water, soluble in dimethylformamide, slightly soluble in ethanol (96 per cent), very slightly soluble in methylene chloride.
• XLogP3: 4.5
• Hydrogen Bond Donor Count: 2
• Hydrogen Bond Acceptor Count: 2
• Rotatable Bond Count: 0
• Exact Mass: 328.251463648
• Heavy Atom Count: 24
• Complexity: 538

Purity/Quality:

99% ^*data from raw suppliers

Stanozolol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xn,Xi
• Hazard Codes: Xn,Xi,T,F
• Statements: 63-38-19-11-61-60
• Safety Statements: 53-22-36/37/39-36-26-45

MSDS Files:

SDS file from LookChem

Total 1 MSDS from other Authors

Useful:

• Canonical SMILES: CC12CCC3C(C1CCC2(C)O)CCC4C3(CC5=C(C4)NN=C5)C
• Isomeric SMILES: C[C@]12CC[C@H]3[C@H]([C@@H]1CC[C@]2(C)O)CC[C@@H]4[C@@]3(CC5=C(C4)NN=C5)C
• Recent ClinicalTrials: Hetrombopag for Low/Intermediate-1 Risk MDS With Thrombocytopenia
• Chemical Composition and Structure: Stanozolol (Stan) is a heterocyclic anabolic androgenic steroid.; Chemical structure: 17β-hydroxy-17α-methyl-5α-androst-2-eno[3,2-c]-pyrazole.
• History and Development: Synthesized in 1959 by Clinton et al.^[1] and remains one of the most detected anabolic steroids in doping control samples^[2].; Classified as an anabolic androgenic steroid.; Developed analytical methods focus on identifying and determining parent drug and/or metabolic products in urine samples.; Early research focused on gas chromatography–mass spectrometry (GC–MS) detection, but liquid chromatography–mass spectrometry (LC–MS) is now preferred.
• Uses: Medical Applications:; Stanozolol has medical applications but is more commonly known for its illicit use in doping.; ; Doping Control:; Used for performance enhancement in athletics.; ; Animal Use:; Also used in veterinary medicine for performance enhancement and growth promotion.
• Mechanism of Action: Acts as an androgen receptor agonist, promoting protein synthesis and muscle growth.
• Pharmacokinetics: Stanozolol is rapidly metabolized in humans and animals.; Major phase-I metabolic products include 3′-hydroxy-stanozolol, 4β-hydroxy-stanozolol, 16β-hydroxy-stanozolol, and 4,16-dihydroxy-stanozolol.; Metabolites are excreted in urine mainly as glucuronide conjugates.^[2]
• Regulatory Status: The prohibition of the drugs by the International Olympic Committee (IOC) in 1974^[1]. Illicit use of stanozolol is prohibited in most sports and is considered a controlled substance in many countries.
• References: [1] Analytical possibilities for the detection of stanozolol and its metabolites (DOI 10.1016/S0003-2670(02)00672-4); [2] Sensitive detection of 3′-hydroxy-stanozolol glucuronide by liquid chromatography–tandem mass spectrometry (DOI 10.1016/j.chroma.2013.01.001)

Technology Process of Stanozolol

There total 2 articles about Stanozolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

→ stanozolol (10418-03-8)

Guidance literature:

With hydrazine;

DOI:10.1021/ja01515a060

Reference yield:

→ 17-methyl-1'(2')H-androstano[3,2-c]pyrazol-17-ol (10418-03-8,22957-48-8,125636-91-1)

Guidance literature:

17β-Hydroxy-17α-methyl-4-androsten<3,2-c>pyrazol, Li, fl. NH3;

DOI:10.1021/jo01045a508