t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Base Information

Chemical Name:t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate
CAS No.:188782-89-0
Molecular Formula:C₂₂H₄₀O₄Si₂
Molecular Weight:424.728
Hs Code.:

Synonyms:t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Suppliers and Price of t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

There total 2 articles about t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 21144-17-2
3-(2'-hydroxy-4'-methoxyphenyl)propanoic acid

: 18162-48-6
tert-butyldimethylsilyl chloride

: 188782-89-0
t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Guidance literature:: With 1H-imidazole; In N,N-dimethyl-formamide; at 60 ℃; for 116h;
DOI:10.1016/S0040-4020(97)00007-0

Reference yield:

: 20921-02-2
7-methoxy-3,4-dihydro-2H-1-benzopyran-2-one

: 188782-89-0
t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

Guidance literature:: Multi-step reaction with 2 steps

1: 1.) KOH / 1.) H₂O, EtOH, 2.) H₂O, EtOH, 150 min

2: 97 percent / imidazole / dimethylformamide / 116 h / 60 °C

With 1H-imidazole; potassium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00007-0

Reference yield:

: 188782-89-0
t-butyldimethylsilyl 3-(2'-t-butyldimethylsilyloxy-4'-methoxyphenyl)propanoate

: 3-(2'-hydroxy-4'-methoxyphenyl)-N-methyl-N-phenylpropanamide

Guidance literature:: Multi-step reaction with 3 steps

1: oxalyl chloride / CH₂Cl₂; dimethylformamide / 0 deg C, 1,5 h; rt, 3 h

2: 4.14 g / diethyl ether; pyridine / 17 h / Ambient temperature

3: 90 percent / MeONa / methanol; CH₂Cl₂ / 0 deg C, 10 min, rt, 30 min

With oxalyl dichloride; sodium methylate; In pyridine; methanol; diethyl ether; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4020(97)00007-0