Methylene violet

Base Information

• Chemical Name: Methylene violet
• CAS No.: 2516-05-4
• Molecular Formula: C14H12N2OS
• Molecular Weight: 256.328
• Hs Code.: 32041900
• European Community (EC) Number: 219-733-4
• NSC Number: 187694
• UNII: Y3G6PD8NRB
• DSSTox Substance ID: DTXSID9062481
• Nikkaji Number: J84.876J
• Wikidata: Q27294218
• ChEMBL ID: CHEMBL1713097
• Mol file: 2516-05-4.mol

Synonyms:7-(dimethylamino)-3H-phenothiazin-3-one;methylene violet

Chemical Property of Methylene violet

Chemical Property:

• Vapor Pressure: 1.38E-07mmHg at 25°C
• Melting Point: 216oC
• Boiling Point: 429.6oC at 760 mmHg。 产品描述 安全性：
• PKA: 5.10±0.20(Predicted)
• Flash Point: 213.6oC
• PSA: 61.44000
• Density: 1.29 g/cm3
• LogP: 2.82730
• Solubility.: Insoluble in water, soluble in ethanol
• XLogP3: 2.1
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 4
• Rotatable Bond Count: 1
• Exact Mass: 256.06703418
• Heavy Atom Count: 18
• Complexity: 464

Purity/Quality:

99% ^*data from raw suppliers

MethyleneViolet(Bernthsen),≥65%(Dyecontent),suitableforHematology&Histology ≥65%(Dyecontent) ^*data from reagent suppliers

Safty Information:

• Safety Statements: 24/25

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CN(C)C1=CC2=C(C=C1)N=C3C=CC(=O)C=C3S2

Technology Process of Methylene violet

There total 22 articles about Methylene violet which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 6.0%

methylene blue (152071-32-4,105504-42-5,121067-62-7,12262-49-6,167498-52-4,6476-03-5,97130-83-1) → methylene violet (2516-05-4)

Guidance literature:

With ammonium hydroxide; silver nitrate; In water; for 1h; Reflux;

Reference yield:

azure A (5283-05-6) → methylene violet (2516-05-4)

Guidance literature:

With sodium hydroxide;

Reference yield:

3,7-bis(dimethylamine)phenothiazonium (807306-71-4) → methylene violet (2516-05-4)

Guidance literature:

With silver(l) oxide;

upstream raw materials:

ethanol

azure A

3,7-bis(dimethylamine)phenothiazonium

water