5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

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Chemical Name:5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile
CAS No.:1018686-65-1
Molecular Formula:C₂₃H₂₆N₆O₃
Molecular Weight:434.498
Hs Code.:

Synonyms:5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

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Chemical Property of 5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

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Technology Process of 5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

There total 1 articles about 5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 74.0%

: 824398-22-3
C₁₈H₁₆ClN₅O₂

: 23356-96-9
(S)-1-Pyrrolidin-2-yl-methanol

: 1018686-65-1
5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

Guidance literature:: With triethylamine; In 1-methyl-pyrrolidin-2-one; at 20 ℃; for 24h;
DOI:10.1016/j.bmc.2007.10.068

Reference yield: 77.0%

: 1018686-65-1
5-cyclopropyl-2-(3,5-dimethoxyphenylamino)-7-((S)-2-hydroxymethylpyrrolidin-1-yl)pyrazolo[1,5-a]pyrimidine-3-carbonitrile

: 1018686-72-0
C₂₃H₂₈N₆O₄

Guidance literature:: With sodium hydroxide; dihydrogen peroxide; In ethanol; dimethyl sulfoxide; at 60 ℃; for 3h;
DOI:10.1016/j.bmc.2007.10.068