4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Base Information

Chemical Name:4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid
CAS No.:1355488-77-5
Molecular Formula:C₁₇H₁₆ClF₂NO₄
Molecular Weight:371.768
Hs Code.:

Synonyms:4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Suppliers and Price of 4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

There total 6 articles about 4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 59.0%

: 1355488-74-2
methyl 4-{[(5-chloro-6-isobutoxypyridin-3-yl)oxy]methyl}-2,5-difluorobenzoate

: 1355488-77-5
4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Guidance literature:: With water; lithium hydroxide; In tetrahydrofuran; at 20 ℃; for 18h; Inert atmosphere;

Reference yield:

: 103877-56-1
2,5-difluoro-4-methyl-benzoyl chloride

: 1355488-77-5
4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Guidance literature:: Multi-step reaction with 4 steps

2: N-Bromosuccinimide / dibenzoyl peroxide / tetrachloromethane / 18 h / 85 °C

3: potassium carbonate / dimethyl sulfoxide / 18 h / 20 °C / Inert atmosphere

4: water; lithium hydroxide / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; water; potassium carbonate; lithium hydroxide; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; dimethyl sulfoxide;

Reference yield:

: 1355488-71-9
methyl 2,5-difluoro-4-methylbenzoate

: 1355488-77-5
4-((5-chloro-6-isobutoxypyridin-3-yloxy)methyl)-2,5-difluorobenzoic acid

Guidance literature:: Multi-step reaction with 3 steps

1: N-Bromosuccinimide / dibenzoyl peroxide / tetrachloromethane / 18 h / 85 °C

2: potassium carbonate / dimethyl sulfoxide / 18 h / 20 °C / Inert atmosphere

3: water; lithium hydroxide / tetrahydrofuran / 18 h / 20 °C / Inert atmosphere

With N-Bromosuccinimide; water; potassium carbonate; lithium hydroxide; dibenzoyl peroxide; In tetrahydrofuran; tetrachloromethane; dimethyl sulfoxide;