p-Aminosalicylic acid hydrazide

Base Information

Chemical Name:p-Aminosalicylic acid hydrazide
CAS No.:6946-29-8
Molecular Formula:C7H9 N3 O2
Molecular Weight:167.167
Hs Code.:
European Community (EC) Number:230-108-5
NSC Number:57125
UNII:ODX97PJ52T
DSSTox Substance ID:DTXSID30219623
Nikkaji Number:J54.307A
Wikidata:Q27285591
Mol file:6946-29-8.mol

Synonyms:6946-29-8;Apacizin;p-Aminosalicylic acid hydrazide;4-amino-2-hydroxybenzenecarbohydrazide;4-amino-2-hydroxybenzohydrazide;4-Aminosalicylic acid hydrazide;Pasdrazide;PAS-Hydrazid;apacizina;4-Aminosalicylohydrazide;4-Aminosalicylsaeurehydrazid;4-Amino-2-hydroxybenzoic acid hydrazide;EINECS 230-108-5;NSC 57125;Salicylic acid, 4-amino-, hydrazide;UNII-ODX97PJ52T;aminosalicylic acid hydrazide;BRN 2965831;ODX97PJ52T;Benzoic acid, 4-amino-2-hydroxy-, hydrazide;NSC57125;NSC-57125;4-14-00-01995 (Beilstein Handbook Reference);Benzoic acid,4-amino-2-hydroxy-, hydrazide;4N2OHPhCON2;WLN: ZMVR DZ BQ;YSZC575;4-Amino-2-oxybenzoyl-hydrazin;SCHEMBL1264279;4-amino-2-hydroxy-benzohydrazide;DTXSID30219623;CHEBI:134800;MFCD01684522;AKOS006241789;HY-W112346;4-Amino-2-hydroxybenzoic acid, hydrazide;LS-144241;CS-0170058;P-AMINOSALICYLIC ACID HYDRAZIDE [MI];E78301;EN300-7821900;12T-0878;Q27285591

Suppliers and Price of p-Aminosalicylic acid hydrazide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
4-amino-2-hydroxybenzenecarbohydrazide
50g
$ 240.00

Matrix Scientific
4-Amino-2-hydroxybenzenecarbohydrazide
500mg
$ 918.00

Biosynth Carbosynth
4-Aminosalicylic acid hydrazide
500 g
$ 250.00

Biosynth Carbosynth
4-Aminosalicylic acid hydrazide
250 g
$ 150.00

Biosynth Carbosynth
4-Aminosalicylic acid hydrazide
100 g
$ 75.00

American Custom Chemicals Corporation
4-AMINO-2-HYDROXYBENZENECARBOHYDRAZIDE 95.00%
5MG
$ 633.99

American Custom Chemicals Corporation
4-AMINO-2-HYDROXYBENZENECARBOHYDRAZIDE 95.00%
10MG
$ 631.85

American Custom Chemicals Corporation
4-AMINO-2-HYDROXYBENZENECARBOHYDRAZIDE 95.00%
1MG
$ 597.89

AK Scientific
p-Aminosalicylicacidhydrazide
250g
$ 252.00

Total 18 raw suppliers

Chemical Property of p-Aminosalicylic acid hydrazide

Chemical Property:

Melting Point:190-200°
Refractive Index:1.5860 (estimate)
Boiling Point:295.73°C (rough estimate)
Density:1.42g/cm³
XLogP3:0.3
Hydrogen Bond Donor Count:4
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:1
Exact Mass:167.069476538
Heavy Atom Count:12
Complexity:174

Purity/Quality:

97% ^*data from raw suppliers

4-amino-2-hydroxybenzenecarbohydrazide ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C1=CC(=C(C=C1N)O)C(=O)NN

Technology Process of p-Aminosalicylic acid hydrazide

There total 5 articles about p-Aminosalicylic acid hydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.4%

: 4136-97-4
methyl 4-aminosalicylate

: 6946-29-8
4-aminosalicylic acid hydrazide

Guidance literature:: With hydrazine hydrate; for 1.5h; Reflux;
DOI:10.1016/j.saa.2012.01.014

Reference yield: 40.0%

: 6059-17-2
ethyl 4-amino-2-hydroxybenzoate

: 6946-29-8
4-aminosalicylic acid hydrazide

Guidance literature:: With hydrazine hydrate; Reflux; Inert atmosphere;
DOI:10.1021/jacs.7b00925

Reference yield:

: 65-49-6
4-Aminosalicylic acid

: 6946-29-8
4-aminosalicylic acid hydrazide

Guidance literature:: Multi-step reaction with 2 steps

1: sulfuric acid

2: hydrazine hydrate

With sulfuric acid; hydrazine hydrate;