N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide

Base Information

• Chemical Name: N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide
• CAS No.: 1225430-96-5
• Molecular Formula: C₅₃H₄₉ClN₂O₈
• Molecular Weight: 877.434

Synonyms:N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide

Chemical Property of N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide

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Technology Process of N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide

There total 1 articles about N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

5-phenylfuran-2-carboxylic acid (52938-97-3) + 2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)acetohydrazide (1225430-44-3) → N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide (1225430-96-5)

Guidance literature:

With 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In water; N,N-dimethyl-formamide; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.bmc.2010.01.073

Reference yield:

N'-(2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)pgenyl)acetyl)-5-phenylfuran-2-carbohydrazide (1225430-96-5) → 2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-5-(5-phenylfuran-2-yl)-1,3,4-thiadiazole (1225430-95-4)

Guidance literature:

With Lawessons reagent; In tetrahydrofuran; Inert atmosphere; Reflux;

DOI:10.1016/j.bmc.2010.01.073

upstream raw materials:

5-phenylfuran-2-carboxylic acid

2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)phenyl)acetohydrazide

Downstream raw materials:

2-(2-chloro-5-((2S,3S,4R,5R,6R)-3,4,5-tris(benzyloxy)-6-(benzyloxymethyl)tetrahydro-2H-pyran-2-yl)benzyl)-5-(5-phenylfuran-2-yl)-1,3,4-thiadiazole

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