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52938-97-3

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52938-97-3 Usage

General Description

5-Phenyl-2-furoic acid is a chemical compound with the molecular formula C11H8O3. It is a phenyl-substituted derivative of furan-2-carboxylic acid, and is also known as 5-phenylfuran-2-carboxylic acid. 5-PHENYL-2-FUROIC ACID is often used as an intermediate in the synthesis of pharmaceuticals and organic compounds. It is a white to off-white crystalline powder, and is slightly soluble in water but more soluble in organic solvents such as ethanol and ethyl acetate. 5-Phenyl-2-furoic acid has potential applications in the development of drugs and agrochemicals, and is also used as a building block in organic synthesis.

Check Digit Verification of cas no

The CAS Registry Mumber 52938-97-3 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 5,2,9,3 and 8 respectively; the second part has 2 digits, 9 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 52938-97:
(7*5)+(6*2)+(5*9)+(4*3)+(3*8)+(2*9)+(1*7)=153
153 % 10 = 3
So 52938-97-3 is a valid CAS Registry Number.
InChI:InChI=1/C11H8O3/c12-11(13)10-7-6-9(14-10)8-4-2-1-3-5-8/h1-7H,(H,12,13)

52938-97-3 Well-known Company Product Price

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  • Aldrich

  • (576301)  5-Phenyl-2-furoicacid  97%

  • 52938-97-3

  • 576301-1G

  • 321.75CNY

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  • Aldrich

  • (576301)  5-Phenyl-2-furoicacid  97%

  • 52938-97-3

  • 576301-5G

  • 672.75CNY

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52938-97-3SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 12, 2017

Revision Date: Aug 12, 2017

1.Identification

1.1 GHS Product identifier

Product name 5-Phenylfuran-2-carboxylic acid

1.2 Other means of identification

Product number -
Other names 5-Phenyl-2-furancarboxylic Acid

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:52938-97-3 SDS

52938-97-3Relevant articles and documents

Furan-2-carboxamide derivative, a novel microtubule stabilizing agent induces mitotic arrest and potentiates apoptosis in cancer cells

Shwetha,Sudhanva, M. Srinivasa,Jagadeesha,Thimmegowda,Hamse, Vivek K.,Sridhar,Thimmaiah,Ananda Kumar,Shobith, Rangappa,Rangappa

, (2021/02/21)

The vital role played by microtubules in the cell division process, marks them as a potential druggable target to decimate cancer. A novel furan-2-carboxamide based small molecule, is a selective microtubule stabilizing agent (MSA) with IC50 ranging from 4 μM to 8 μM in different cancer cell lines. Inhibition of tubulin polymerization or stabilization of tubulin polymers abrogates chromosomal segregation during cell division, results in cell cycle arrest and leads to cell death due to the delayed repair mechanism. A novel furan-2-carboxamide based small molecule exhibited potent anti-proliferative and anti-metastatic property In-Vitro against the panel of cancer cells. Annexin V-FITC/PI, double staining reveals potent cytotoxic effect of SH09 against HeLa cells. FACS analysis displays induction of G2/M arrest and accumulation of subG1 population of cells upon treatment with SH09. Molecular docking study unveils SH09 binding affinity to the Taxol binding pocket of tubulin proteins and MM-GBSA also confirms strong binding energies of SH09 with tubulin proteins.

Design, synthesis, and electrophysiological evaluation of NS6740 derivatives: Exploration of the structure-activity relationship for alpha7 nicotinic acetylcholine receptor silent activation

Pismataro, Maria Chiara,Horenstein, Nicole A.,Stokes, Clare,Quadri, Marta,De Amici, Marco,Papke, Roger L.,Dallanoce, Clelia

, (2020/08/19)

The α7 nicotinic acetylcholine receptor (nAChR) silent agonists, able to induce receptor desensitization and promote the α7 metabotropic function, are emerging as new promising therapeutic anti-inflammatory agents. Herein, we report the structure–activity

Synthesis and bioactivity of phenyl substituted furan and oxazole carboxylic acid derivatives as potential PDE4 inhibitors

Lin, Yinuo,Ahmed, Wasim,He, Min,Xiang, Xuwen,Tang, Riyuan,Cui, Zi-Ning

, (2020/10/02)

In this present study, a series of 5-phenyl-2-furan and 4-phenyl-2-oxazole derivatives were designed and synthesized as phosphodiesterase type 4 (PDE4) inhibitors. In vitro results showed that the synthesized compounds exhibited considerable inhibitory ac

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