(S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol

Base Information

• Chemical Name: (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol
• CAS No.: 1609493-09-5
• Molecular Formula: C₂₇H₂₉NO₄
• Molecular Weight: 431.532
• Mol file: 1609493-09-5.mol

Synonyms:(S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol

Chemical Property of (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol

There total 1 articles about (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 87.0%

bis(p-methoxyphenyl)methanone (90-96-0) + (-)-(S)-2-(2-bromo-phenyl)-4-isopropyl-4,5-dihydro-oxazole (148836-24-2) → (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol (1609493-09-5)

Guidance literature:

(-)-(S)-2-(2-bromo-phenyl)-4-isopropyl-4,5-dihydro-oxazole; With n-butyllithium; In tetrahydrofuran; hexane; at -89 ℃; for 0.833333h;

bis(p-methoxyphenyl)methanone; In tetrahydrofuran; hexane; at -89 - 20 ℃; for 16h;

DOI:10.1039/c4cc01060d

Reference yield: 88.0%

dichloro bis(acetonitrile) palladium(II) (21264-30-2,90243-59-7,14592-56-4) + (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol (1609493-09-5) → C27H29Cl2NO4Pd

Guidance literature:

In dichloromethane; at 20 ℃; for 1h;

DOI:10.1039/c4cc01060d

Reference yield: 68.0%

2-fluoropyridine (372-48-5) + (S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol (1609493-09-5) → (S,Z)-N-(3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)-3-methyl-1-(pyridin-2-yloxy)butan-2-amine (1609493-13-1)

Guidance literature:

(S,Z)-2-((3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)amino)-3-methylbutan-1-ol; With sodium hydride; In tetrahydrofuran; mineral oil; for 0.0833333h;

2-fluoropyridine; In tetrahydrofuran; mineral oil; at 20 ℃;

DOI:10.1039/c4cc01060d

upstream raw materials:

bis(p-methoxyphenyl)methanone

(-)-(S)-2-(2-bromo-phenyl)-4-isopropyl-4,5-dihydro-oxazole

Downstream raw materials:

(S,Z)-N-(3,3-bis(4-methoxyphenyl)isobenzofuran-1(3H)-ylidene)-3-methyl-1-(pyridin-2-yloxy)butan-2-amine