(2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid

Base Information

• Chemical Name: (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid
• CAS No.: 108272-49-7
• Molecular Formula: C₁₁H₁₃N₃O₇S
• Molecular Weight: 331.306
• Mol file: 108272-49-7.mol

Synonyms:(2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid

Chemical Property of (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid

There total 4 articles about (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.24%

1-(4'-nitrobenzenesulphonyl)-5-oxopyrrolidine-2-carboxylic acid → (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid (108272-49-7)

Guidance literature:

With hydrogenchloride; ammonia; In water;

DOI:10.1016/j.ejmech.2017.09.052

Reference yield:

4-Nitrobenzenesulfonyl chloride (98-74-8) → (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid (108272-49-7)

Guidance literature:

Multi-step reaction with 3 steps

1: sodium hydroxide / water

2: acetyl chloride / 2 h / Reflux

3: hydrogenchloride; ammonia / water

With hydrogenchloride; ammonia; acetyl chloride; sodium hydroxide; In water;

DOI:10.1016/j.ejmech.2017.09.052

Reference yield:

2-N-(4'-nitrobenzenesulphonyl)-L(+)-glutamic acid (6328-28-5) → (2S)-5-amino-5-oxo-2-[(nitrobenzene-4-ylsulfonyl)amino]pentanoic acid (108272-49-7)

Guidance literature:

Multi-step reaction with 2 steps

1: acetyl chloride / 2 h / Reflux

2: hydrogenchloride; ammonia / water

With hydrogenchloride; ammonia; acetyl chloride; In water;

DOI:10.1016/j.ejmech.2017.09.052

upstream raw materials:

2-N-(4'-nitrobenzenesulphonyl)-L(+)-glutamic acid

4-Nitrobenzenesulfonyl chloride

L-glutamic acid