C₂₂H₂₄N₂O₂S

Base Information

• Chemical Name: C₂₂H₂₄N₂O₂S
• CAS No.: 1379799-58-2
• Molecular Formula: C₂₂H₂₄N₂O₂S
• Molecular Weight: 380.511
• Mol file: 1379799-58-2.mol

Synonyms:C₂₂H₂₄N₂O₂S

Chemical Property of C₂₂H₂₄N₂O₂S

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₂₂H₂₄N₂O₂S

There total 1 articles about C₂₂H₂₄N₂O₂S which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-allyl-1-(phenylsulfonyl)-3-indolecarbaldehyde (752212-01-4) → C22H24N2O2S (1379799-58-2)

Guidance literature:

Multi-step reaction with 2 steps

1: acetic acid / ethanol; dichloromethane / 20 °C / Inert atmosphere

2: tetrahydrofuran; diethyl ether / -78 - 20 °C / Inert atmosphere

With acetic acid; In tetrahydrofuran; diethyl ether; ethanol; dichloromethane;

DOI:10.1016/j.tet.2012.04.022

Reference yield:

(Z)-2-bromobut-2-enoic acid (5405-34-5) + C22H24N2O2S (1379799-58-2) → 2-allyl-3-[(Z)-1-(N-methyl-2-bromobut-2-enamido)-3-butenyl]-1-(phenylsulfonyl)indole (1379799-59-3)

Guidance literature:

With 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane; at 20 ℃; for 60h; Inert atmosphere;

DOI:10.1016/j.tet.2012.04.022

Reference yield:

C22H24N2O2S (1379799-58-2) → 10-((Z)-N-methyl-2-bromobut-2-enamido)-5-(phenylsulfonyl)-9,10-dihydro-6H-cyclohepta[b]indole (1379799-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / dichloromethane / 60 h / 20 °C / Inert atmosphere

2: tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride / dichloromethane / 3 h / Inert atmosphere; Reflux

With tricyclohexylphosphine[1,3-bis(2,4,6-trimethylphenyl)-4,5-dihydroimidazol-2-ylidine][benzylidene]ruthenium(II) dichloride; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; In dichloromethane;

DOI:10.1016/j.tet.2012.04.022

upstream raw materials:

2-allyl-1-(phenylsulfonyl)-3-indolecarbaldehyde

Downstream raw materials:

10-((Z)-N-methyl-2-bromobut-2-enamido)-5-(phenylsulfonyl)-9,10-dihydro-6H-cyclohepta[b]indole

2-allyl-3-[(Z)-1-(N-methyl-2-bromobut-2-enamido)-3-butenyl]-1-(phenylsulfonyl)indole