3-ethyl-5-phenyl-2-oxoazolidinone

Base Information

• Chemical Name: 3-ethyl-5-phenyl-2-oxoazolidinone
• CAS No.: 1032817-99-4
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Mol file: 1032817-99-4.mol

Synonyms:3-ethyl-5-phenyl-2-oxoazolidinone

Chemical Property of 3-ethyl-5-phenyl-2-oxoazolidinone

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

Useful:

Technology Process of 3-ethyl-5-phenyl-2-oxoazolidinone

There total 12 articles about 3-ethyl-5-phenyl-2-oxoazolidinone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

1-ethyl-2-phenylaziridine (4164-24-3) + C9H4NO4(1-)*K(1+) (40794-76-1) → 3-ethyl-5-phenyl-2-oxoazolidinone (1032817-99-4)

Guidance literature:

With 1,4-diazabicyclo[2.2.2]octan-1-ium iodide; In methanol; at 40 ℃; for 24h; Autoclave;

DOI:10.1002/cssc.201400133

Reference yield: 66.0%

1-ethyl-2-phenylaziridine (4164-24-3) + carbon dioxide (124-38-9,18923-20-1) → 3-ethyl-4-phenyl-2-oxoazolidinone (1067194-00-6) + 3-ethyl-5-phenyl-2-oxoazolidinone (1032817-99-4)

Guidance literature:

With L-proline; at 110 ℃; for 8h; under 97509.8 Torr; regioselective reaction; Autoclave;

DOI:10.1080/00397911.2010.521903

Reference yield:

bis(phenyl) carbonate (102-09-0) + (R/S)-2-(ethylamino)-1-phenylethanol (5300-22-1) → 3-ethyl-5-phenyl-2-oxoazolidinone (1032817-99-4)

Guidance literature:

With sodium hydride; In tetrahydrofuran; at 20 ℃; for 6h;

DOI:10.1016/j.molcatb.2015.08.004

upstream raw materials:

1-ethyl-2-phenylaziridine

carbon dioxide

styrene

(2-bromo-1-phenylethyl)dimethylsulphonium bromide