2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine

Base Information

Chemical Name:2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine
CAS No.:23023-17-8
Molecular Formula:C₁₂H₁₉NO₂
Molecular Weight:209.288
Hs Code.:
European Community (EC) Number:856-302-5
DSSTox Substance ID:DTXSID80482825
Nikkaji Number:J1.630.284H
Wikidata:Q82319639

Synonyms:23023-17-8;2-(3,4-dimethoxyphenyl)-2-methylpropan-1-amine;Benzeneethanamine, 3,4-dimethoxy-beta,beta-dimethyl-;2-(3,4-Dimethoxyphenyl)-2-methylpropylamine;MFCD09881831;SCHEMBL557886;DTXSID80482825;CYRFLEMTQNARBO-UHFFFAOYSA-N;AKOS010214640;EN300-70578;2-(3,4-Dimethoxy-phenyl)-2-methyl-propylamine;Z725146538

Suppliers and Price of 2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 6 raw suppliers

Chemical Property of 2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:209.141578849
Heavy Atom Count:15
Complexity:194

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)(CN)C1=CC(=C(C=C1)OC)OC

Technology Process of 2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine

There total 3 articles about 2-(3,4-Dimethoxyphenyl)-2-methylpropan-1-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 44.5%

: 23023-16-7
2‐(3,4‐dimethoxyphenyl)‐2‐methylpropionitrile

: 23023-17-8
2-(3,4-dimethoxyphenyl)-2-methyl-propylamine

Guidance literature:: With lithium aluminium tetrahydride; In tetrahydrofuran; at 20 ℃; for 24.5h; Cooling with ice;

Reference yield: 21.0%

: 23023-17-8
2-(3,4-dimethoxyphenyl)-2-methyl-propylamine

Guidance literature:

Reference yield:

: 93-17-4
3,4-dimethoxyphenylacetonitrile

: 23023-17-8
2-(3,4-dimethoxyphenyl)-2-methyl-propylamine

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium diisopropyl amide / tetrahydrofuran; n-heptane; ethylbenzene / 1 h / -78 °C / Inert atmosphere

1.2: 1.5 h / -78 - 20 °C / Inert atmosphere

2.1: lithium aluminium tetrahydride / tetrahydrofuran / 1 h / 0 - 90 °C / Inert atmosphere

With lithium aluminium tetrahydride; lithium diisopropyl amide; In tetrahydrofuran; n-heptane; ethylbenzene;
DOI:10.1002/anie.201805060