2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

Base Information

Chemical Name:2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide
CAS No.:1179983-74-4
Molecular Formula:C₁₉H₁₆F₂N₂O₃
Molecular Weight:358.344
Hs Code.:

Synonyms:2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

Chemical Property:

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Technology Process of 2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

There total 1 articles about 2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 52061-51-5
4-Benzyloxyindol-3-yl-N,N-dimethylglyoxylamide

: 1179983-74-4
2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

Guidance literature:: With Selectfluor; In acetonitrile; at 20 ℃;

Reference yield: 47.0%

: 1179983-74-4
2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

: 1179983-75-5
2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethylethanamine

Guidance literature:: With lithium aluminium tetrahydride; In 1,4-dioxane; Reflux;

Reference yield:

: 1179983-74-4
2-(4-benzyloxy-5,7-difluoro-1H-indol-3-yl)-N,N-dimethyl-2-oxoacetamide

: 1179983-76-6
2-(4-(benzyloxy)-5,7-difluoro-1-methyl-1H-indol-3-yl)-N,N-dimethylethanamine

Guidance literature:: Multi-step reaction with 2 steps

1: lithium aluminium tetrahydride / 1,4-dioxane / Reflux

2: sodium hydride / N,N-dimethyl-formamide / 0 °C

With lithium aluminium tetrahydride; sodium hydride; In 1,4-dioxane; N,N-dimethyl-formamide;