tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

Base Information

Chemical Name:tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate
CAS No.:1352805-48-1
Molecular Formula:C₂₀H₂₁ClFN₃O₂
Molecular Weight:389.857
Hs Code.:

Synonyms:tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

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Chemical Property of tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

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Technology Process of tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

There total 7 articles about tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

: 1352805-47-0
tert-butyl {1-[1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

: 1352805-48-1
tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

Guidance literature:: With N-chloro-succinimide; In N,N-dimethyl-formamide;

Reference yield:

: 1352805-43-6
N-methoxy-N-methyl-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

: 1352805-48-1
tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

Guidance literature:: Multi-step reaction with 5 steps

1: pyridine / dichloromethane; methanol

2: methylmagnesium bromide; ammonium chloride / tetrahydrofuran

3: ammonium acetate; sodium cyanoborohydride / methanol; acetonitrile

4: triethylamine; sodium hydrogencarbonate / tetrahydrofuran

5: N-chloro-succinimide / N,N-dimethyl-formamide

With pyridine; ammonium acetate; N-chloro-succinimide; methylmagnesium bromide; ammonium chloride; sodium cyanoborohydride; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;

Reference yield:

: 136818-50-3
7-azaindole-2-carboxylic acid

: 1352805-48-1
tert-butyl {1-[3-chloro-1-(3-fluorophenyl)-1H-pyrrolo[2,3-b]pyridin-2-yl]ethyl}carbamate

Guidance literature:: Multi-step reaction with 6 steps

1: triethylamine / N,N-dimethyl-formamide

2: pyridine / dichloromethane; methanol

3: methylmagnesium bromide; ammonium chloride / tetrahydrofuran

4: ammonium acetate; sodium cyanoborohydride / methanol; acetonitrile

5: triethylamine; sodium hydrogencarbonate / tetrahydrofuran

6: N-chloro-succinimide / N,N-dimethyl-formamide

With pyridine; ammonium acetate; N-chloro-succinimide; methylmagnesium bromide; ammonium chloride; sodium cyanoborohydride; sodium hydrogencarbonate; triethylamine; In tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;