Technology Process of C30H26N2O2
There total 9 articles about C30H26N2O2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
2-(2-(pyridin-3-yl)benzofuran-5-yl)acetic acid;
With
1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran;
at 20 ℃;
for 0.5h;
(2,4-dimethylphenyl)(phenyl)methanamine hydrochloride;
With
benzotriazol-1-ol; triethylamine;
In
tetrahydrofuran;
at 20 ℃;
for 24h;
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux
2.1: triphenylphosphine / dichloromethane / 0.25 h / 0 °C
2.2: 3 h / 0 °C
3.1: potassium phosphate; copper(l) iodide / tetrahydrofuran / 12 h / 80 °C / Inert atmosphere
4.1: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / toluene; water; ethanol / 6 h / 80 °C / Inert atmosphere
5.1: sodium hydroxide / water / 0.5 h / 80 °C
5.2: 0 °C
6.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / 0.5 h / 20 °C
6.2: 24 h / 20 °C
With
potassium phosphate; copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; sodium hydroxide; magnesium chloride;
In
tetrahydrofuran; ethanol; dichloromethane; water; toluene; acetonitrile;
- Guidance literature:
-
Multi-step reaction with 7 steps
1.1: sulfuric acid / 0 - 80 °C
2.1: triethylamine; magnesium chloride / acetonitrile / Inert atmosphere; Reflux
3.1: triphenylphosphine / dichloromethane / 0.25 h / 0 °C
3.2: 3 h / 0 °C
4.1: potassium phosphate; copper(l) iodide / tetrahydrofuran / 12 h / 80 °C / Inert atmosphere
5.1: sodium carbonate; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2 / toluene; water; ethanol / 6 h / 80 °C / Inert atmosphere
6.1: sodium hydroxide / water / 0.5 h / 80 °C
6.2: 0 °C
7.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / tetrahydrofuran / 0.5 h / 20 °C
7.2: 24 h / 20 °C
With
potassium phosphate; copper(l) iodide; dichloro(1,1'-bis(diphenylphosphanyl)ferrocene)palladium(II)*CH2Cl2; sulfuric acid; sodium carbonate; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; triethylamine; triphenylphosphine; sodium hydroxide; magnesium chloride;
In
tetrahydrofuran; ethanol; dichloromethane; water; toluene; acetonitrile;