Technology Process of (2S,3R,4R,5R,6R)-3-Azido-6-azidomethyl-4,5-bis-benzyloxy-2-phenylsulfanyl-tetrahydro-pyran
There total 4 articles about (2S,3R,4R,5R,6R)-3-Azido-6-azidomethyl-4,5-bis-benzyloxy-2-phenylsulfanyl-tetrahydro-pyran which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
phenyl 2,6-diazido-2,6-dideoxy-1-thio-β-D-glucopyranoside;
With
t-butyl ammonium iodide; sodium hydride;
In
N,N-dimethyl-formamide;
for 1h;
benzyl bromide;
In
N,N-dimethyl-formamide;
at 20 ℃;
for 1h;
DOI:10.1039/b505865a
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 89 percent / NaN3 / dimethylformamide / 18 h / Heating
2.1: NaH; tert-butyl ammonium iodide / dimethylformamide / 1 h
2.2: 31 percent / dimethylformamide / 1 h / 20 °C
With
sodium azide; t-butyl ammonium iodide; sodium hydride;
In
N,N-dimethyl-formamide;
DOI:10.1039/b505865a
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: 3.58 g / pyridine / 8 h
2.1: 89 percent / NaN3 / dimethylformamide / 18 h / Heating
3.1: NaH; tert-butyl ammonium iodide / dimethylformamide / 1 h
3.2: 31 percent / dimethylformamide / 1 h / 20 °C
With
pyridine; sodium azide; t-butyl ammonium iodide; sodium hydride;
In
N,N-dimethyl-formamide;
DOI:10.1039/b505865a