(1S,2R)-2-methoxycyclohexanol

Base Information

• Chemical Name: (1S,2R)-2-methoxycyclohexanol
• CAS No.: 174390-40-0
• Molecular Formula: C₇H₁₄O₂
• Molecular Weight: 130.187
• Mol file: 174390-40-0.mol

Synonyms:(1S,2R)-2-methoxycyclohexanol

Chemical Property of (1S,2R)-2-methoxycyclohexanol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (1S,2R)-2-methoxycyclohexanol

There total 6 articles about (1S,2R)-2-methoxycyclohexanol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2-methoxycyclohexanone (7429-44-9) → (1S,2R)-2-methoxycyclohexanol (174390-40-0) + (1R, 2S)-2-methoxycyclohexanol (155320-77-7) + trans-2-methoxycyclohexanol (7429-40-5,7429-41-6,113625-71-1,134108-68-2,134108-92-2,2979-24-0)

Guidance literature:

With Amberlite IRA-900; hydrogen; Pt/Al₂O₃; (-)-4-[(R)-((2S)-5-ethyl-1-azabicyclo[2.2.2]oct-2-yl)-methoxy-methyl]-quinoline; In acetic acid; at 25 ℃; for 0.266667h; under 45004.5 Torr; Further Variations:; Catalysts; Solvents; Reagents; Product distribution; Kinetics;

DOI:10.1002/1615-4169(200207)344:5<511::AID-ADSC511>3.0.CO;2-D

Reference yield:

2-methoxycyclohexanone (7429-44-9) → (1S,2S)-2-methoxycyclohexanol (134108-92-2) + trans-2-methoxycyclohexanol (113625-71-1) + (1S,2R)-2-methoxycyclohexanol (174390-40-0) + (1R, 2S)-2-methoxycyclohexanol (155320-77-7)

Guidance literature:

With potassium tert-butylate; hydrogen; [(Cl)2Ru(Pphenyl₃)(ligand L₂)]; In ethanol; toluene; at 25 ℃; for 20h; under 60006 Torr;

Reference yield:

2-methoxycyclohexanone (7429-44-9) → (1S,2R)-2-methoxycyclohexanol (174390-40-0) + (1R, 2S)-2-methoxycyclohexanol (155320-77-7) + (2S)-2-methoxycyclohexanone (155320-76-6) + (R)-2-methoxycyclohexanone

Guidance literature:

With hydrogen; RuH(η1-BH4)[(S)-2,2'-bis(di-3,5-xylylphosphino)-1,1'-binaphthyl][(S,S)-1,2-diphenylethylenediamine]; In isopropyl alcohol; at 23 - 25 ℃; for 1h; under 6080.41 Torr;

DOI:10.1021/ja026136+

upstream raw materials:

2-methoxycyclohexanone

1R,2R-trans-diphenyl-1,2-ethanediamine