1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

Base Information

Chemical Name:1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan
CAS No.:1104608-07-2
Molecular Formula:C₁₇H₂₅N₅O₄
Molecular Weight:363.417
Hs Code.:

Synonyms:1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

Chemical Property:

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MSDS Files:: SDS file from LookChem

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Technology Process of 1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

There total 1 articles about 1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: (4S)-2,3-epoxy-4-(methoxymethoxy)pentanal

: 1104608-06-1
2,6-diamino-4-(cyclohexyloxy)-5-nitrosopyrimidine

: 1104608-07-2
1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

Guidance literature:: 2,6-diamino-4-(cyclohexyloxy)-5-nitrosopyrimidine; With 5%-palladium/activated carbon; hydrogen; In acetonitrile; at 20 ℃;

(4S)-2,3-epoxy-4-(methoxymethoxy)pentanal; With hydrogenchloride; In water; acetonitrile; for 1h;

With dihydrogen peroxide; iodine; In water; acetonitrile; for 12h; regioselective reaction;
DOI:10.3987/COM-08-S(N)99

Reference yield: 82.0%

: 1104608-07-2
1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

: 22150-76-1
biopterin

Guidance literature:: With hydrogenchloride; In methanol; water; at 50 ℃; for 23h;
DOI:10.3987/COM-08-S(N)99

Reference yield:

: 1104608-07-2
1-(2-amino-4-cyclohexyloxypteridin-6-yl)-1R,2S-1-hydroxy-2-(methoxymethoxy)propan

: 17094-01-8
sepiapterin

Guidance literature:: Multi-step reaction with 3 steps

1.1: tetrapropylammonium perruthennate; 4-methylmorpholine N-oxide / acetonitrile / 1 h / 60 °C / Inert atmosphere; Molecular sieve

2.1: hydrogenchloride / methanol; water / 3 h / 50 °C

2.2: pH 7

3.1: hydrogen; Pd/C (Ph₂S); triethylamine / methanol; water / 3 h / 40 °C

With hydrogenchloride; tetrapropylammonium perruthennate; Pd/C (Ph₂S); hydrogen; 4-methylmorpholine N-oxide; triethylamine; In methanol; water; acetonitrile;