2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime

Base Information

• Chemical Name: 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime
• CAS No.: 1430841-94-3
• Molecular Formula: C₂₁H₂₂Cl₂N₂O₂
• Molecular Weight: 405.324
• Mol file: 1430841-94-3.mol

Synonyms:2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime

Chemical Property of 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime

There total 4 articles about 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

2-(2,4-dichlorobenzyloxy)benzaldehyde (52803-60-8) + O-(quinuclidin-3-yl)hydroxylamine hydrogen chloride → 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime (1430841-94-3)

Guidance literature:

With sodium carbonate; In methanol; at 20 ℃; for 3h; Inert atmosphere;

DOI:10.1016/j.ejmech.2012.12.033

Reference yield:

O-(quinuclidin-3-yl)hydroxylamine (1430882-55-5,738558-73-1) → 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime (1430841-94-3)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride / water / Inert atmosphere

2: sodium carbonate / methanol / 3 h / 20 °C / Inert atmosphere

With hydrogenchloride; sodium carbonate; In methanol; water;

DOI:10.1016/j.ejmech.2012.12.033

Reference yield:

2-(quinuclidin-3-yloxy)isoindoline-1,3-dione (1430841-71-6) → 2-(2,4-dichlorobenzyloxy)benzaldehyde O-quinuclidin-3-yl oxime (1430841-94-3)

Guidance literature:

Multi-step reaction with 3 steps

1: hydrazine hydrate / ethanol / 3 h / 80 °C / Inert atmosphere

2: hydrogenchloride / water / Inert atmosphere

3: sodium carbonate / methanol / 3 h / 20 °C / Inert atmosphere

With hydrogenchloride; sodium carbonate; hydrazine hydrate; In methanol; ethanol; water;

DOI:10.1016/j.ejmech.2012.12.033

upstream raw materials:

2-(2,4-dichlorobenzyloxy)benzaldehyde

2-(quinuclidin-3-yloxy)isoindoline-1,3-dione

O-(quinuclidin-3-yl)hydroxylamine

3-quinuclidinol