2-Bromo-3-methylbutanenitrile

Base Information

Chemical Name:2-Bromo-3-methylbutanenitrile
CAS No.:25117-57-1
Molecular Formula:C₅H₈BrN
Molecular Weight:162.029
Hs Code.:
European Community (EC) Number:828-197-6
DSSTox Substance ID:DTXSID301306949

Synonyms:2-bromo-3-methylbutanenitrile;25117-57-1;DTXSID301306949;AKOS017529144;EN300-1239804

Suppliers and Price of 2-Bromo-3-methylbutanenitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 3 raw suppliers

Chemical Property of 2-Bromo-3-methylbutanenitrile

Chemical Property:

XLogP3:2.1
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:1
Rotatable Bond Count:1
Exact Mass:160.98401
Heavy Atom Count:7
Complexity:89.5

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(C)C(C#N)Br

Technology Process of 2-Bromo-3-methylbutanenitrile

There total 1 articles about 2-Bromo-3-methylbutanenitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 615-82-7
DL-Leucyl-glycin

: 25117-57-1
2-bromo-3-methylbutyronitrile

: 625-28-5
Isovaleronitrile

: 56-40-6,18875-39-3,25718-94-9
glycine

Guidance literature:: N-DL-leucyl-glycine;

Reference yield: 79.0%

: 25117-57-1
2-bromo-3-methylbutyronitrile

: 100-58-3
phenylmagnesium bromide

: 161967-83-5
(R)-3-methyl-2-phenylbutanenitrile

Guidance literature:: phenylmagnesium bromide; With zinc dimethoxide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

2-bromo-3-methylbutyronitrile; With (1,2-dimethoxyethane)dichloronickel(II); N,N,N,N,-tetramethylethylenediamine; (4S,4'S)-2,2'-(cyclopentane-1,1-diyl)bis(4-iso-propyl-4,5-dihydrooxazole); In tetrahydrofuran; at -78 ℃; for 48h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja303442q

Reference yield: 75.0%

: 25117-57-1
2-bromo-3-methylbutyronitrile

: 100-58-3
phenylmagnesium bromide

: 174411-82-6
(S)-3-methyl-2-phenylbutanenitrile

Guidance literature:: phenylmagnesium bromide; With zinc dimethoxide; In tetrahydrofuran; at 20 ℃; for 1h; Inert atmosphere;

2-bromo-3-methylbutyronitrile; With (1,2-dimethoxyethane)dichloronickel(II); N,N,N,N,-tetramethylethylenediamine; (4R,4'R)-2,2'-(cyclopentane-1,1-diyl)bis(4-isopropyl-4,5-dihydrooxazole); In tetrahydrofuran; at -78 ℃; for 48h; optical yield given as %ee; enantioselective reaction; Inert atmosphere;
DOI:10.1021/ja303442q