Technology Process of (2S,3S,4R,Z)-3-(benzyloxy)oct-5-ene-1,2,4-triol
There total 6 articles about (2S,3S,4R,Z)-3-(benzyloxy)oct-5-ene-1,2,4-triol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
(3aR,5R,6S,6aR)-6-(benzyloxy)-5-((Z)-but-1-en-1-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole;
With
acetic acid;
In
water;
at 70 ℃;
for 8h;
With
sodium tetrahydroborate;
In
tetrahydrofuran; water;
at 0 - 20 ℃;
for 8h;
DOI:10.1016/j.tetlet.2013.12.017
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: sodium hydride; tetra-(n-butyl)ammonium iodide / tetrahydrofuran / 10 h / 70 °C
2.1: acetic acid; water / 5 h / 55 °C
3.1: sodium periodate / water; methanol / 0.75 h
4.1: n-butyllithium / tetrahydrofuran / 20 h / -78 - 20 °C
5.1: acetic acid / water / 8 h / 70 °C
5.2: 8 h / 0 - 20 °C
With
sodium periodate; n-butyllithium; water; tetra-(n-butyl)ammonium iodide; sodium hydride; acetic acid;
In
tetrahydrofuran; methanol; water;
4.1: |Wittig Olefination;
DOI:10.1016/j.tetlet.2013.12.017
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: n-butyllithium / tetrahydrofuran / 20 h / -78 - 20 °C
2.1: acetic acid / water / 8 h / 70 °C
2.2: 8 h / 0 - 20 °C
With
n-butyllithium; acetic acid;
In
tetrahydrofuran; water;
1.1: |Wittig Olefination;
DOI:10.1016/j.tetlet.2013.12.017
![(3aR,5R,6S,6aR)-6-(benzyloxy)-5-((Z)-but-1-en-1-yl)-2,2-dimethyltetrahydrofuro[2,3-d][1,3]dioxole](/Databaselist/images/loading.webp)
